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Dr. Vatz is in private practice in Arlington Heights, III.
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Alpha1-Adrenergic Blockers: Do They Have a Place in the Prophylaxis of Migraine?
Article first published online: 19 JAN 2002
DOI: 10.1046/j.1526-4610.1997.3702107.x
Additional Information
How to Cite
Vatz, K. A. (1997), Alpha1-Adrenergic Blockers: Do They Have a Place in the Prophylaxis of Migraine?. Headache: The Journal of Head and Face Pain, 37: 107–108. doi: 10.1046/j.1526-4610.1997.3702107.x
Publication History
- Issue published online: 19 JAN 2002
- Article first published online: 19 JAN 2002
- Accepted for publication June 15, 1996.
- Abstract
- Cited By
Keywords:
- migraine;
- prophylaxis;
- alpha1-adrenergic;
- terazosin;
- doxazosin
On the basis of the author’s personal experience with migraine, and occasional reports in the literature suggesting that alpha1-adrenergic blocking drugs may have a beneficial effect in the prophylaxis of migraine, 10 patients with migraine in a general neurology practice were placed on either terazosin or doxazosin. A decrease in migraine frequency or severity or both was seen in all but I patient, but 5 patients discontinued the drug due to side effects. No serious adverse reactions were reported. This anecdotal experience with the alpha 1 -adrenergic blockers warrants a controlled, double-blind study of this class of drugs for the prophylaxis of migraine.