Dr. Vatz is in private practice in Arlington Heights, III.
Alpha1-Adrenergic Blockers: Do They Have a Place in the Prophylaxis of Migraine?
Version of Record online: 19 JAN 2002
Headache: The Journal of Head and Face Pain
Volume 37, Issue 2, pages 107–108, February, 1997
How to Cite
Vatz, K. A. (1997), Alpha1-Adrenergic Blockers: Do They Have a Place in the Prophylaxis of Migraine?. Headache: The Journal of Head and Face Pain, 37: 107–108. doi: 10.1046/j.1526-4610.1997.3702107.x
- Issue online: 19 JAN 2002
- Version of Record online: 19 JAN 2002
- Accepted for publication June 15, 1996.
- Cited By
On the basis of the author’s personal experience with migraine, and occasional reports in the literature suggesting that alpha1-adrenergic blocking drugs may have a beneficial effect in the prophylaxis of migraine, 10 patients with migraine in a general neurology practice were placed on either terazosin or doxazosin. A decrease in migraine frequency or severity or both was seen in all but I patient, but 5 patients discontinued the drug due to side effects. No serious adverse reactions were reported. This anecdotal experience with the alpha 1 -adrenergic blockers warrants a controlled, double-blind study of this class of drugs for the prophylaxis of migraine.