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Pattern-Reversal Visual Evoked Potentials in Migraineurs With or Without Visual Aura


Dr. Özden Sener, Ankara University Faculty of Medicine, Department of Neurology, Ankara, Turkey.


To determine the possible electrophysiologic changes in migraineurs with or without visual aura, we investigatedpattern-reversal visual evoked potentials in 39 patients. We compared the mean P100 latency and amplitude of 16patients with aura, 23 patients without aura, and 17 age- and sex-matched normal subjects. There were no significantdifferences between groups. There was no correlation between age and the parameters in any group. However, in 7 of23 patients without aura, the P100 latency was longer than the mean control value + 2 SD. The mean disease duration inthis subgroup was significantly longer than the means of the remaining 16 patients without aura or the patients with aura(P<0.05 for each). This suggests the possibility that P100 latency prolongation is a consequence, but not an entitycaused by the pathogenetic mechanism of the disease from the beginning.