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REFERENCES

  • 1
    Brodie MJ, French JA. Management of epilepsy in adolescents and adults. Lancet 2000;356: 3239.
  • 2
    Vining EP, Freeman JM, Ballaban-Gil K, et al. A multicenter study of the efficacy of the ketogenic diet. Arch Neurol 1998;55: 14337.
  • 3
    Livingston S. Dietary treatment of epilepsy. In: LivingstonS, ed. Comprehensive management of epilepsy in infancy, childhood and adolescence. Springfield , IL : Charles CThomas, 1972: 378405.
  • 4
    Freeman JM, Vining EPG, Pillas DJ, et al. The efficacy of the ketogenic diet–1998: a prospective evaluation of intervention in 150 children. Pediatrics 1998;102: 35863.
  • 5
    Wilder RM. The effects of ketonemia on the course of epilepsy. Mayo Clin Bull 1921;2: 3078.
  • 6
    Cahill GF. Starvation in man. Clin Endocrinol Metab 1976;5: 397415.
  • 7
    Huttenlocher P. Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy. Pediatr Res 1976;10: 53640.
  • 8
    Freeman JM, Freeman JB, Kelly MT. The ketogenic diet: a treatment for epilepsy. 3rd ed. New York : Demos Medical Publishing, 2000.
  • 9
    Uhlemann ER, Neims AH. Anticonvulsant properties of the ketogenic diet in mice. J Pharmacol Exp Ther 1972;180: 2318.
  • 10
    Otani K, Yamatodani A, Wada H, et al. Effect of ketogenic diet on convulsive threshold and brain monoamine levels in young mice. No Tu Hattatsu 1984;16: 196204.
  • 11
    Appleton DB, De Vivo DC. An animal model for the ketogenic diet. Epilepsia 1974;15: 2117.
  • 12
    Hori A, Tandon P, Holmes GL, et al. Ketogenic diet: effects on expression of kindled seizures and behavior in adult rats. Epilepsia 1997;38: 7508.
  • 13
    Lothman EW, Stringer JL, Bertram EH. The dentate gyrus as a control point for seizures in the hippocampus and beyond. Epilepsy Res 1992;7(suppl):30113.
  • 14
    McNamara JO. Emerging insights into the genesis of epilepsy. Nature 1999;399(suppl):A1522.
  • 15
    Tuff LP, Racine RJ, Adamec R. The effects of kindling on GABA-mediated inhibition in the dentate gyrus of the rat, I: paired-pulse depression. Brain Res 1983;277: 7990.
  • 16
    De Jonge M, Racine RJ. The development and decay of kindling-induced increases in paired-pulse depression in the dentate gyrus. Brain Res 1987;412: 31828.
  • 17
    Stringer JL, Lothman EW. Maximal dentate gyrus activation: characteristics and alterations after repeated seizures. J Neurophysiol 1989;62: 13643.
  • 18
    Bough KJ, Emmi A, Rejniak SX, et al. Paired-pulse inhibition and maximal dentate activation protocols suggest decreased excitability in ketogenic diet-fed rats in vivo. Epilepsia 2001;42(suppl 7):264.
  • 19
    Rogers AE. Nutrition. In: BakerHJ, LindseyJR, WeisbrothSH, eds. The laboratory rat. Orlando , FL : Academic Press, 1979: 12352.
  • 20
    Bough KJ, Eagles DA. A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat. Epilepsia 1999;40: 13843.
  • 21
    Sloviter RS. Feedforward and feedback inhibition of hippocampal principal cell activity evoked by perforant path stimulation: GABA-mediated mechanisms that regulate excitability in vivo. Hippocampus 1991;1: 3140.
  • 22
    Stringer JL, Williamson JM, Lothman EW. Induction of paroxysmal discharges in the dentate gyrus: frequency dependence and relationship to afterdischarge production. J Neurophysiol 1989;62: 12635.
  • 23
    Stringer JL, Lothman EW. Maximal dentate activation: a tool to screen compounds for activity against limbic seizures. Epilepsy Res 1990;5: 16976.
  • 24
    Likhodii SS, Musa K, Mendonca A, et al. Dietary fat, ketosis, and seizure resistance in rats on the ketogenic diet. Epilepsia 2000;41: 140019.
  • 25
    Rho JM, Kim DW, Robbins CA, et al. Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet. Epilepsy Res 1999;37: 23340.
  • 26
    Buckmaster PS, Schwartzkroin PA. Hyperexcitability in the dentate gyrus of the epileptic mongolian gerbil. Epilepsy Res 1994;18: 238.
  • 27
    Muller-Schwarze AB, Tandon P, Liu Z, et al. Ketogenic diet reduces spontaneous seizures and mossy fiber sprouting in the kainic acid model. Neuroreport 1999;10: 151722.
  • 28
    Su SW, Cilio MR, Sogawa Y, et al. Timing of ketogenic diet initiation in an experimental epilepsy model. Brain Res Dev Brain Res 2000;125: 1318.
  • 29
    Croll SD, Suri C, Compton DL, et al. Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex. Neuroscience 1999;93: 1491506.
  • 30
    Michelson HB, Kapur J, Lothman EW. Reduction of paired pulse inhibition in the CA1 region of the hippocampus by pilocarpine in naive and in amygdala-kindled rats. Exp Neurol 1989;104: 26471.
  • 31
    Salin PA, Prince DA. Electrophysiological mapping of GABAA receptor-mediated inhibition in adult rat somatosensory cortex. J Neurophysiol 1996;75: 1589600.
  • 32
    Stafstrom CE, Wang C, Jensen FE. Electrophysiological observations in hippocampal slices from rats treated with the ketogenic diet. Dev Neurosci 1999;21: 3939.
  • 33
    Kapur J, Stringer JL, Lothman EW. Evidence that repetitive seizures in the hippocampus cause a lasting reduction of GABAergic inhibition. J Neurophysiol 1989;61: 41726.
  • 34
    Erecinska M, Nelson D, Daikhin Y, et al. Regulation of GABA level in rat brain synaptosomes: fluxes through enzymes of the GABA shunt and effects on glutamate, calcium, and ketone bodies. J Neurochem 1996;67: 232534.
  • 35
    Yudkoff M, Daikhin Y, Nissim I, et al. Brain amino acid metabolism and ketosis. J Neurosci Res 2001;66: 27281.
  • 36
    Stringer JL, Lothman EW. Use of maximal dentate activation to study the effect of drugs on kindling and kindled responses. Epilepsy Res 1990;6: 1806.
  • 37
    Stringer JL. A comparison of topiramate and acetazolamide on seizure duration and paired-pulse inhibition in the dentate gyrus of the rat. Epilepsy Res 2000;40: 14753.
  • 38
    Stringer JL, Taylor CP. The effects of gabapentin in the rat hippocampus are mimicked by two structural analogs, but not by nimodipine. Epilepsy Res 2000;41: 15562.
  • 39
    Greene AE, Todorova MT, McGowan R, et al. Caloric restriction inhibits seizure susceptibility in epileptic EL mice by reducing blood glucose. Epilepsia 2001;42: 13718.
  • 40
    Bough KJ, Matthews PJ, Eagles DA. A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion. Epilepsy Res 2000;38: 10514.
  • 41
    Stringer JL. Alterations in both excitation and inhibition occur before the onset of seizure activity in the hippocampus. Epilepsy Res 1993;16: 99109.
  • 42
    Stringer JL. Repeated seizures cause a generalized increase in excitability in the hippocampus. Neurosci Lett 1993;150: 2236.
  • 43
    Stringer JL. Repeated seizures increase GFAP and vimentin in the hippocampus. Brain Res 1996;717: 14753.
  • 44
    Stringer JL, Agarwal KS, Dure LS. Is cell death necessary for hippocampal mossy fiber sprouting? Epilepsy Res 1997;27: 6776.
  • 45
    White HS. Animal models of epileptogenesis. Neurology 2002;59(suppl 5):S714.
  • 46
    Kashiwaya Y, Takeshima T, Mori N, et al. d-β-Hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease. Proc Natl Acad Sci U S A 2000;97: 54404.
  • 47
    Bruce-Keller AJ, Umberger G, McFall R, et al. Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann Neurol 1999;45: 815.