Summary: Purpose: To review the factors influencing prognosis of epilepsy in this era of antiepileptic drugs and surgical treatment.
Methods: Systematic review of peer-reviewed literature.
Results: The prognosis depends on many factors; aetiology, age of onset, number of siezures at onset, the natural history of the condition, and the influence of treatment. However, between 70 and 80% of people developing epilepsy will go into long-term remission, usually within the first 5 years.
Discussion: Prognosis in epilepsy is the prospect of attaining complete seizure freedom once a pattern of recurrent epileptic seizures has been established. Well-designed prospective cohort studies using standard outcome measures need to be conducted, especially in non-Western cultures.