Linda Ann Sherman, MD, Resident, Department of Pathology, New England Medical Center Hospital.
Altered blood group expression in a patient with congenital rubella infection
Article first published online: 5 MAR 2003
Volume 24, Issue 3, pages 267–269, May-June 1984
How to Cite
Sherman, L.A., Silberstein, L.E. and Berkman, E.M. (1984), Altered blood group expression in a patient with congenital rubella infection. Transfusion, 24: 267–269. doi: 10.1046/j.1537-2995.1984.24384225037.x
- Issue published online: 5 MAR 2003
- Article first published online: 5 MAR 2003
- Revision received November 3, 1983; and accepted November 4, 1983.
An infant with probable congenital rubella infection developed altered blood group expression. This was noted at 4 months of age. The child's blood was typed on seven separate occasions during the first 8 weeks of life as type A, but on repeat testing, her cells failed to agglutinate with anti-A and anti-A,B typing serum. The A antigen was present, however, because an eluate made after incubating her red cells with anti-A contained anti-A, and A antigen was demonstrated on buccal mucosa cells. Altered expression of blood group A (loss of agglutinability) has occurred previously only in association with hematologic malignancy.