Geir Hetland, MD, Blood Bank and Department of Immunology, Ullevaal Hospital.
Posttransfusion hepatitis B transmitted by blood from a hepatitis B surface antigen-negative hepatitis B virus carrier
Article first published online: 5 MAR 2003
Volume 30, Issue 5, pages 431–432, June 1990
How to Cite
Larsen, J., Hetland, G. and Skaug, K. (1990), Posttransfusion hepatitis B transmitted by blood from a hepatitis B surface antigen-negative hepatitis B virus carrier. Transfusion, 30: 431–432. doi: 10.1046/j.1537-2995.1990.30590296376.x
- Issue published online: 5 MAR 2003
- Article first published online: 5 MAR 2003
- Received for publication July 25, 1989; revision received November 6, 1989, and accepted November 11, 1989
A female blood donor at our institution was implicated in three cases of clinical posttransfusion hepatitis B. She had given blood 25 times in 8 years. Twenty-seven recipients were followed up, and about one-half of those who were still living had serologic markers of hepatitis B virus (HBV) infection. The donor was repeatedly negative for hepatitis B surface antigen (HBsAg) and antibody, but she had high titers of antibody to hepatitis B core antigen. We conclude that blood from this HBsAg-negative blood donor was capable of transmitting hepatitis B.