Present address: INSERM U.311, Etablissement Français du Sang-Alsace, 10 rue Spielmann, B.P. N°36, 67065 Strasbourg Cedex, France.
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Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice
Article first published online: 3 JAN 2003
DOI: 10.1046/j.1538-7836.2003.00003.x
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How to Cite
Hechler, B., Zhang, Y., Eckly, A., Cazenave, J.-P., Gachet, C. and Ravid, K. (2003), Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice. Journal of Thrombosis and Haemostasis, 1: 155–163. doi: 10.1046/j.1538-7836.2003.00003.x
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Present address: INSERM U.311, Etablissement Français du Sang-Alsace, 10 rue Spielmann, B.P. N°36, 67065 Strasbourg Cedex, France.
Publication History
- Issue published online: 3 JAN 2003
- Article first published online: 3 JAN 2003
- Received 19 March 2002, revised 24 July 2002, accepted 29 July 2002
References
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 9
- 10
- 11
- 12
- 13
- 14
- 15, , , , , . Conditions influencing release of granule contents from human platelets in citrated plasma induced by ADP or the thrombin receptor activating peptide SFLLRN. direct measurement of percent release of beta- thromboglobulin and assessment by flow cytometry of P-selectin expression. Am J Hematol 1996; 52: 288–94.
- 16
- 17
- 18
- 19
- 20, , , , . L'agrégation plaquettaire: outil d'investigation clinique et d'étude pharmacologique. Méthodologie Ann Biol Clin 1983; 41: 167–79.
- 21
- 22
- 23
- 24
- 25
- 26
- 27
- 28
- 29
- 30
- 31
- 32
- 33
- 34
- 35
- 36
- 37, , , , , , . Deficiency of (33P)2MeS–ADP binding sites on platelets with secretion defect, normal granule stores and normal thromboxane A2 production. Evidence that ADP potentiates platelet secretion independently of the formation of large platelet aggregates and thromboxane A2 production. Thromb Haemost 1997; 77: 986–90.
- 38, , , , . Platelets from a patient heterozygous for the defect of P2CYC receptors for ADP have a secretion defect despite normal thromboxane A2 production and normal granule stores: further evidence that some cases of platelet ‘primary secretion defect’ are heterozygous for a defect of P2CYC receptors. Arterioscler Thromb Vasc Biol 2000; 20: E101–6.

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