Dr. Shimizu was supported by the Japan Heart Foundation/Pfizer Grant for Cardiovascular Disease Research, Kanae Foundation, Kato Memorial Bio-science Research Foundation, Japanese Cardiovascular Research Founda-tion, and Research Grant for Cardiovascular Diseases (11C-1) from the Ministry of Health and Welfare, Japan.
Paradoxic Abbreviation of Repolarization in Epicardium of the Right Ventricular Outflow Tract During Augmentation of Brugada-Type ST Segment Elevation
Version of Record online: 13 AUG 2003
© Futura Publishing Company, Inc. 2001
Journal of Cardiovascular Electrophysiology
Volume 12, Issue 12, pages 1418–1421, December 2001
How to Cite
SHIMIZU, W., AIBA, T., KURITA, T. and KAMAKURA, S. (2001), Paradoxic Abbreviation of Repolarization in Epicardium of the Right Ventricular Outflow Tract During Augmentation of Brugada-Type ST Segment Elevation. Journal of Cardiovascular Electrophysiology, 12: 1418–1421. doi: 10.1046/j.1540-8167.2001.01418.x
- Issue online: 13 AUG 2003
- Version of Record online: 13 AUG 2003
- Manuscript received 23 July 2001; Accepted for publication 3 October 2001.
- Cited By
- brugada syndrome;
- ST elevation epicardium;
- action potential;
ST Elevation in Brugada Syndrome. We report the case of a 53-year-old Japanese man with a typical Brugada-like ECG in whom epicardial and endocardial activation-recovery intervals (ARI) in the right ventricular outflow tract (RVOT) were simultaneously measured by recording unipolar electrograms from the Pathfinder catheter introduced in the great cardiac vein as well as from the multielectrode basket catheter deployed in the RVOT. Epicardial ARI in the RVOT was abbreviated paradoxically at the beat of augmented ST segment elevation in lead V2 after a long pause or after pilsicainide injection. Endocardial ARI in the RVOT and epicardial ARI in the left ventricle were prolonged or were not changed. Our data support the hypothesis that heterogenous response of repolarization across the ventricular wall in the RVOT is responsible for accentuation of ST segment elevation in the right precordial leads.