Supported in part by grants from the Japanese Society of Cardiac Pacing and Electrophysiology and the Gunma Prefecture Government, and by the Don Nouse Arrhythmia Research Fund.
Pulmonary Vein Isolation: Comparison of Bipolar and Unipolar Electrograms at Successful and Unsuccessful Ostial Ablation Sites
Version of Record online: 12 AUG 2003
© Futura Publishing Company, Inc. 2002
Journal of Cardiovascular Electrophysiology
Volume 13, Issue 1, pages 13–19, January 2002
How to Cite
TADA, H., ORAL, H., WASMER, K., GREENSTEIN, R., PELOSI, F., KNIGHT, B. P., STRICKBERGER, S. A. and MORADY, F. (2002), Pulmonary Vein Isolation: Comparison of Bipolar and Unipolar Electrograms at Successful and Unsuccessful Ostial Ablation Sites. Journal of Cardiovascular Electrophysiology, 13: 13–19. doi: 10.1046/j.1540-8167.2002.00013.x
- Issue online: 12 AUG 2003
- Version of Record online: 12 AUG 2003
- Manuscript received 23 August 2001; Accepted for publication 21 November 2001.
- Cited By
- atrial fibrillation;
- pulmonary vein;
- unipolar electrogram
Electrogram Analysis.Introduction: No prior studies have quantitatively analyzed the characteristics of bipolar or unipolar electrograms that may be helpful in identifying successful ostial ablation sites in patients with atrial fibrillation undergoing segmental pulmonary vein isolation.
Methods and Results: The characteristics of bipolar and unipolar electrograms recorded at 185 successful and 120 unsuccessful ostial pulmonary venous ablation sites were analyzed in 21 patients with atrial fibrillation. A decapolar Lasso catheter was positioned near the ostia of the pulmonary veins, and a conventional ablation catheter was used to deliver radiofrequency energy at individual ostial sites where pulmonary vein potentials were recorded. With both bipolar and unipolar recordings, the only timing parameter that distinguished successful from unsuccessful ostial ablation sites was the timing of the electrogram recorded by the ablation catheter relative to the earliest pulmonary vein potential recorded by the Lasso catheter. With both bipolar and unipolar recordings, electrograms demonstrated a larger amplitude at successful than at unsuccessful ablation sites. Unipolar electrograms had a steeper intrinsic deflection at successful than at unsuccessful ostial ablation sites. The morphologies of the unipolar electrograms recorded by the ablation catheter and by the contiguous electrode of the Lasso catheter usually were identical.
Conclusion: In patients undergoing segmental isolation of the pulmonary veins, unipolar recordings provide more information than bipolar recordings helpful in distinguishing successful from unsuccessful ostial ablation sites. Furthermore, unipolar recordings, but not bipolar recordings, allow accurate localization of the position of the ablation catheter relative to the electrodes of the Lasso catheter.