• 1
    Noborg U, Gusdal A, Horal P, Lindh M. Levels of viraemia in subjects with serological markers of past or chronic hepatitis B virus infection. Scand J Infect Dis 2000; 32:249252.MEDLINE
  • 2
    Paterlini P, Poussin K, Kew M, Franco D, Bréchot C. Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma. Hepatology 1995; 21:313321.MEDLINE
  • 3
    Cacciola I, Pollicino T, Squadrito G, Cerenzia G, Villari D, De Franchis R, Santantonio T, et al. Quantification of intrahepatic hepatitis B virus (HBV) DNA in patients with chronic HBV infection. Hepatology 2000; 31:507512.MEDLINE
  • 4
    Shafritz DA, Lieberman HM, Isselbacher KJ, Wands JR. Monoclonal radioimmunoassay for hepatitis B surface antigen: demonstration of hepatitis B virus DNA or related sequences in serum and viral epitopes in immune complexes. Proc Natl Acad Sci U S A 1982; 79:5675.MEDLINE
  • 5
    Wands JR, Bruns RR, Carlson RI, Ware A, Menitove JE, Isselbacher KJ. Monoclonal IgM radioimmmunoassay for hepatitis B surface antigen: light binding activity in serum that is unreactive with conventional antibodies. Proc Natl Acad Sci U S A 1982; 79:12771281.MEDLINE
  • 6
    Pol S, Thiers V, Nalpas B, Degos F, Gazengel C, Carnot F, Tiollais P, et al. Monoclonal anti-HBs antibodies radioimmunoassay and serum HBV-DNA hybridization as diagnostic tools of HBV infection: relative prevalence among HBsAg-negative alcoholics, patients with chronic hepatitis or hepatocellular carcinomas and blood donors. Eur J Clin Invest 1987; 17:515521.MEDLINE
  • 7
    Bréchot C, Lugassy C, Dejean A, Pontisso P, Thiers V, Berthelot P, Tiollais P. Hepatitis B virus DNA in infected human tissues viral hepatitis. In: VyasGN, DienstagJL, HoofnagleJH (eds). Viral Hepatitis and Liver Diseases. New York, Grune and Stratton, 1984;395409.
  • 8
    Bréchot C. Applications of molecular biology to the diagnosis of viral hepatitis. In: ZuckermanA, ThomasH (eds). Viral Hepatitis. Third ed. London: Churchill Livingstone, 1998:585604.
  • 9
    Bläckberg J, Kidd-Ljunggren K. Occult hepatitis B virus after acute self-limited infection persisting for 30 years without sequence variation. J Hepatol 2000; 33:992997.MEDLINE
  • 10
    Michalak TI. Occult persistence and lymphotropism of hepadnaviral infection: insights from the woodchuck viral hepatitis model. Immunol Rev 2000; 174:98111.MEDLINE
  • 11
    Bréchot C, Degos F, Lugassy C, Thiers V, Zafrani S, Franco D, Bismuth G. Hepatitis B virus DNA in patients with chronic liver disease and negative tests for hepatitis B surface antigen. N Engl J Med 1985; 312:270276.MEDLINE
  • 12
    Coursaget P, Bourdil C, Adamowicz P, Chotard J, Diop Mar I, Yvonnet B, Mevelec MN, et al. HBsAg positive reactivity in man not due to hepatitis B virus. Lancet 1987; 12:13541357.
  • 13
    Wands JR, Fujita YK, Isselbacher KJ, Schellekens H, Dazza MC, Thiers V, Tiollais P, et al. Identification and transmission of a hepatitis B virus-related variants. Proc Natl Acad Sci U S A 1986; 83:66086612.MEDLINE
  • 14
    Thiers V, Nakajima E, Kremsdorf D, Mack D, Schellekens H, Driss F, Goudeau A, et al. Transmission of hepatitis from hepatitis-B-seronegative subjects. Lancet 1988; ii:12731276.
  • 15
    Baginski I, Chemin I, Hantz O. Transmission of serologically silent hepatitis B virus along with hepatitis C virus in two cases of posttransfusion hepatitis. Transfusion 1992; 32:215220.MEDLINE
  • 16
    Chazouillères O, Mamish D, Kim M, Carey K, Ferrell L, Roberts JP, Ascher NL, et al. “Occult” hepatitis B virus as source of infection in liver transplant recipients. Lancet 1994; 343:142146.MEDLINE
  • 17
    Roche B, Samuel D, Gigou M, Feray C, Virot V, Schmets L, David MF, et al. De novo and apparent de novo hepatitis B virus infection after liver transplantation. J Hepatol 1997; 26:517526.MEDLINE
  • 18
    Tokeshi S, Sata M, Tanikawa K. Detection of serum HBV DNA and anti-HCV antibody in HBsAg seronegative patients with hepatocellular carcinoma in Japan. Kansenshogaku Zasshi 1996; 70:103107.MEDLINE
  • 19
    Wachs ME, Amend WJ, Ascher NL, Bretan PN, Emond J, Lake JR, Melzer JS, et al. The risk of transmission of hepatitis B from HBsAg(−), HBcAb(+), HBIgM(−) organ donors. Transplantation 1995; 59:230234.MEDLINE
  • 20
    Dickson RC, Everhart JE, Lake JR, Wei Y, Seaberg EC, Wiesner RH, Zetterman RK, et al. Transmission of hepatitis B by transplantation of livers from donors positive for antibody to hepatitis B core antigen. The National Institute of Diabetes and Digestive and Kidney Diseases Liver Transplantation Database. Gastroenterology 1997; 113:16681674.MEDLINE
  • 21
    Uemoto S, Sugiyama K, Marusawa H, Inomata Y, Asonuma K, Egawa H, Kiuchi T, et al. Transmission of hepatitis B virus from hepatitis B core antibody-positive donors in living related liver transplants. Transplantation 1998; 65:494499.MEDLINE
  • 22
    Mason A, Xu L, Guo L, Kuhns M, Perrillo R. Molecular basis for persistent hepatitis B virus infection in the liver after clearance of serum hepatitis B surface antigen. Hepatology 1998; 6:17361742.
  • 23
    Marusawa H, Uemoto S, Hijikata M, Ueda Y, Tanaka K, Shimothono K, Chiba T. Latent hepatitis B virus infection in healthy individuals with antibodies to hepatitis B core antigen. Hepatology 2000; 31:488495.MEDLINE
  • 24
    Lauré F, Zaguri D, Saimot AG, Gallo RC, Hahn BH, Bréchot C. Hepatitis B virus DNA sequences in lymphoid cells from patients with AIDS and AIDS-related complex. Science 1985; 229:561563.MEDLINE
  • 25
    Pasquinelli C, Lauré F, Chatenaud L, Beauvin G, Gazengee C, Bismuth H, Degos F, et al. Hepatitis B virus DNA in mononuclear blood cells. J Hepatol 1986; 3:95103.MEDLINE
  • 26
    Cabrerizo M, Bartolome J, Caramelo C, Barril G, Carreno V. Molecular analysis of hepatitis B virus DNA in serum and peripheral blood mononuclear cells from hepatitis B surface antigen-negative cases. Hepatology 2000; 32:116123.MEDLINE
  • 27
    Kew M FY, Takahashi H, Coppins A, Wands J. Comparison between polyclonal and first and second generation monoclonal radioimmunoassays in the detection of hepatitis B surface antigen in patients with hepatocellular carcinoma. Hepatology 1986; 6:636639.MEDLINE
  • 28
    Rehermann B, Ferrari C, Pasquinelli C, Chisari FV. The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response. Nat Med 1996; 2:11041108.MEDLINE
  • 29
    Carman W, Thomas H, Domingo E. Viral genetic variation—hepatitis-B virus as a clinical example. Lancet 1993; 341:349353.MEDLINE
  • 30
    Brunetto M, Rodriguez U, Bonino F. Hepatitis B virus mutants. Intervirology 1999; 42:6980.MEDLINE
  • 31
    Zuckerman AJ, Zuckerman JN. Molecular epidemiology of hepatitis B virus mutants. J Med Virol 1999; 58:193195.MEDLINE
  • 32
    Carman WF, Van Deursen FJ, Mimms LT, Hardie D, Coppola R, Decker R, Sanders R. The prevalence of surface antigen variants of hepatitis B virus in Papua New Guinea, South Africa, and Sardinia. Hepatology 1997; 26:16581666.MEDLINE
  • 33
    Grethe S, Monazahian M, Bohme I, Thomssen R. Characterization of unusual escape variants of hepatitis B virus isolated from a hepatitis B surface antigen-negative subject. J Virol 1998; 72:76927696.MEDLINE
  • 34
    Oon CJ, Chen WN, Zhao Y, Teng SW, Leong AL. Detection of hepatitis B surface antigen mutants and their integration in human hepatocellular carcinoma. Cancer Lett 1999; 136:9599.MEDLINE
  • 35
    Hou J, Karayiannis P, Waters J, Luo K, Liang C, Thomas HC. A unique insertion in the S gene of surface antigen negative hepatitis B virus Chinese carriers. Hepatology 1995; 21:273278.MEDLINE
  • 36
    Kato J, Hasegawa K, Torii N, Yamauchi K, Hayashi N. A molecular analysis of viral persistence in surface antigen-negative chronic hepatitis B. Hepatology 1996; 23:389395.MEDLINE
  • 37
    Weinberger KM, Bauer T, Bohm S, Jilg W. High genetic variability of the group-specific a-determinant of hepatitis B virus surface antigen (HBsAg) and the corresponding fragment of the viral polymerase in chronic virus carriers lacking detectable HBsAg in serum. J Gen Virol 2000; 81:11651174.MEDLINE
  • 38
    Bahn A, Gerner P, Martine U, Bortolotti F, Wirth S. Detection of different viral strains of hepatitis B virus in chronically infected children after seroconversion from HBsAg to anti-HBs indicating viral persistence. J Hepatol 1997; 27:973978.MEDLINE
  • 39
    Kremsdorf D, Garreau F, Duclos H, Thiers V, Schellekens H, Petit MA, Bréchot C. Complete nucleotide sequence and viral envelope protein expression of a hepatitis B virus DNA derived from a hepatitis B surface antigen seronegative patient. J Hepatol 1993; 18:244250.MEDLINE
  • 40
    Preisler Adams S, Schlayer HJ, Peters T, Hettler F, Gerok W, Rasenack J. Sequence analysis of hepatitis B virus DNA in immunologically negative infection. Arch Virol 1993; 133:385396.MEDLINE
  • 41
    Uchida T, Aye TT, Shimojima M, Gotoh K, Shikata T. Full-length nucleotide sequence of a hepatitis B virus (HBV) mutant isolated from a patient with acute hepatitis who did not exhibit serological markers for HBV infection. Int Hepatol Commun 1994; 2:7073.
  • 42
    Hino K, Katoh Y, Vardas E, Carman WF, Okita K. The effect of introduction of universal childhood vaccination on the prevalence of serologically negative hepatitis B virus infection and the selection of immune escape variants in a developing country [Abstract]. Hepatology 1999; 30:557 (300A).
  • 43
    Paterlini P, Poussin K, De Mitri S, Kew M, Grigioni W, Franco D, Bréchot C. Rate of persistance, structure, and expression of HBV genome in HCC developing in HBsAg-negative patients. In: NishiokaK, SuzukiH, MishiroS, OdaT (eds). Viral Hepatitis and Liver Disease. Second Edition. Tokyo: Springer-Verlag 1994;757762.
  • 44
    Uchida T, Shimojima M, Gotoh K, Shikata T, Tanaka E, Kiyosawa K. “Silent” hepatitis B virus mutants are responsible for non-A, non-B, non-C, non-D, non-E hepatitis. Microbiol Immunol 1994; 38:281285.MEDLINE
  • 45
    Feitelson M, Lega L, Guo J, Resti M, Rossi ME, Azzari C, Blumberg BS, et al. Pathogenesis of posttransfusion viral hepatitis in children with beta-thalassemia. Hepatology 1994; 19:558568.MEDLINE
  • 46
    Poussin K, Diennes H, Sirma H, Urban S, Beaugrand M, Schirmacher P, Bréchot C, et al. Expression of mutated hepatitis B virus X gene in human hepatocellular carcinomas. Int J Cancer 1999; 80:497505.MEDLINE
  • 47
    Fukuda R, Ishimura N, Niigaki M, Hamamoto S, Satoh S, Tanaka S, Kushiyama Y, et al. Serologically silent hepatitis B virus coinfection in patients with hepatitis C virus-associated chronic liver disease: clinical and virological significance. J Med Virol 1999; 58:201207.MEDLINE
  • 48
    Uchida T, Aye TT, Becker SO, Hirashima M, Shikata T, Komine F, Moriyama M, et al. Detection of precore/core-mutant hepatitis B virus genome in patients with acute or fulminant hepatitis without serological markers for recent HBV infection. J Hepatol 1993; 18:369372.MEDLINE
  • 49
    Guidotti LG, Rochford R, Chung J, Shapiro M, Purcell R, Chisari FV. Viral clearance without destruction of infected cells during acute HBV infection. Science 1999; 284:825829.MEDLINE
  • 50
    Chisari FV. Rous-Whipple Award Lecture. Viruses, immunity, and cancer: lessons from hepatitis B. Am J Pathol 2000; 156:11171132.MEDLINE
  • 51
    Penna A, Artini M, Cavalli A, Levrero M, Bertoletti A, Pilli M, Chisari FV, et al. Long-lasting memory T cell responses following self-limited acute hepatitis B. J Clin Invest 1996; 98:11851194.MEDLINE
  • 52
    Rehermann B, Lau D, Hoofnagle JH, Chisari FV. Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection. J Clin Invest 1996; 97:16551665.MEDLINE
  • 53
    Ackerman Z, Gazitt LY, Wands JR, Bréchot C, Kew M, Shouval D. Unmasking of circulating hepatitis B surface antigen (HBsAg) following removal of immune complex from serum of HBsAg-negative patients with chronic liver diseases and hepatocellular carcinoma. In: ZuckermanAL (ed). Viral Hepatitis and Liver Disease. First Edition. New York: Alan R. Liss, 1988:783785.
  • 54
    Joller-Jemelka HI, Wicki AN, Grob PJ. Detection of HBs antigen in “anti-HBc alone” positive sera. J Hepatol 1994; 21:269272.MEDLINE
  • 55
    Yotsuyanagi H, Yasuda K, Iino S, Moriya K, Shintani Y, Fujie H, Tsutsumi T, et al. Persistent viremia after recovery from self-limited acute hepatitis B. Hepatology 1998; 27:13771382.MEDLINE
  • 56
    Lee SD, Lo KJ, Tsai YT, Wu JC, Wu TC. HBsAg carrier infants with serum anti-HBc negativity. Hepatology 1989; 9:102104.MEDLINE
  • 57
    Moller B, Hopf U, Stemerowicz R, Henze G, Gelderblom H. HBcAg expressed on the surface of circulating Dane particles in patients with hepatitis B virus infection without evidence of anti-HBc formation. Hepatology 1989; 10:179185.MEDLINE
  • 58
    Nalpas B, Pourcel C, Felman G, Housset C, Tiollais P, Bréchot C, Berthelot P, et al. Chronic alcohol intoxication decreases the serum level of hepatitis B surface antigen in transgenic mice. J Hepatol 1992; 15:118124.MEDLINE
  • 59
    Ganne-Carrié N, Kremsdorf D, Garreau F, Thévenin M, Petit MA, Nalpas B, Bréchot C. Effects of ethanol on hepatitis B virus pre-S/S gene expression in the human hepatocellular carcinoma derived HepG2 hepatitis B DNA positive cell line. J Hepatol 1995; 23:153159.MEDLINE
  • 60
    Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ, Study FtRepD. The risk of transfusion-transmitted viral infections. N Engl J Med 1996; 334:16851690.MEDLINE
  • 61
    Pillonel J, Saura C, Courouce AM. [Prevalence of HIV, HTLV, and hepatitis B and C viruses in blood donors in France, 1992-1996]. Transfus Clin Biol 1998; 5:305312.MEDLINE
  • 62
    Hoofnagle JH, Seefe LB, Bales ZB, Zimmerman HJ. Type B hepatitis after transfusion with blood containing antibody to hepatitis B core antigen. N Engl J Med 1978; 298:13791383.MEDLINE
  • 63
    Thiers V, Lunel-Fabiani F, Valla D, Opolon P, Bréchot C. Post transfusional anti-HCV negative non-A non-B hepatitis: serological and polymerase chain reaction analysis for hepatitis C and hepatitis B viruses. J Hepatol 1993; 18:3439.MEDLINE
  • 64
    Sun R, Jayakar H, Yeh S, Mendoza M, Wisbeski MH, Iszczyszyn W, Dragon EA. Experience with PCR screening. Dev Biol Stand 2000; 102:8191.MEDLINE
  • 65
    Defoort JP, Martin M, Casano B, Prato S, Camilla C, Fert V. Simultaneous detection of multiplex-amplified human immunodeficiency virus type 1 RNA, hepatitis C virus RNA, and hepatitis B virus DNA using a flow cytometer microsphere-based hybridization assay. J Clin Microbiol 2000; 38:10661071.MEDLINE
  • 66
    Otake K, Nishioka K. Nucleic acid amplification testing of hepatitis B virus. Lancet 2000; 355:1460.MEDLINE
  • 67
    Liang TJ, Baruch Y, Ben-Porath E. Hepatitis B virus infection in patients with idiopathic liver disease. Hepatology 1991; 13:10441051.MEDLINE
  • 68
    Zhang YY, Hansson BG, Kuo LS, Widell A, Nordenfelt E. Hepatitis B virus DNA in serum and liver is commonly found in Chinese patients with chronic liver disease despite the presence of antibodies to HBsAg. Hepatology 1993; 17:538544.MEDLINE
  • 69
    Coursaget P, Le cann P, Leboulleux D, Diop MT, Bao O, Coll AM. Detection of hepatitis B virus DNA by polymerase chain reaction in HBsAg negative Senegalese patients suffereing from cirrhosis or primary liver cancer. FEMS Microbiol Lett 1991; 83:3538.
  • 70
    Berasain C, Betes M, Panizo A, Ruiz J, Herrero JI, Civeira MP, Prieto J. Pathological and virological findings in patients with persistent hypertransaminasaemia of unknown aetiology. Gut 2000; 47:429435.MEDLINE
  • 71
    Chisari FV. Cytotoxic T cells and viral hepatitis. J Clin Invest 1997; 99:14721477.MEDLINE
  • 72
    Seeger C, Mason WS. Hepatitis B virus biology. Microbiol Mol Biol Rev 2000; 64:5168.MEDLINE
  • 73
    Soussan P, Garreau F, Zylberberg H, Ferray C, Bréchot C, Kremsdorf D. In vivo expression of a new hepatitis B virus protein encoded by a spliced RNA. J Clin Invest 2000; 105:5560.MEDLINE
  • 74
    Bréchot C, Trepo C, Ninova-Bradistilova D, Goudeau A, Degott C, Maupas P, Potet F, et al. Hepatitis B core antigen in hepatocytes of patients with chronic active hepatitis. Dig Dis Sci 1980; 25:593596.MEDLINE
  • 75
    Han KH, Hollinger FB, Noonan CA, Solomon H, Klintmalm GB, Genta RM, Yoffe B. Southern-blot analysis and simultaneous in situ detection of hepatitis B virus-associated DNA and antigens in patients with end-stage liver disease. Hepatology 1993; 18:10321038.MEDLINE
  • 76
    Uchida T, Shimojima S, Gotoh K, Shikata T, Mima S. Pathology of livers infected with “silent” hepatitis B virus mutant. Liver 1994; 14:251256.MEDLINE
  • 77
    Bréchot C, Hadchouel J, Scotto M, Fonck F, Potet GN, Tiollais P. State of hepatitis B virus DNA in hepatocytes of patients with HBsAg positive and HBsAg negative liver diseases. PNAS 1981; 78:39063910.MEDLINE
  • 78
    Urashima T, Saigo K, Kobayashi S, Imaseki H, Matsubara H, Koide Y, Asano T, et al. Identification of hepatitis B virus integration in hepatitis C virus-infected hepatocellular carcinoma tissues. J Hepatol 1997; 26:771778.MEDLINE
  • 79
    Bréchot C, Gozuacik D, Murakami Y, Paterlini-Brechot P. Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Semin Cancer Biol 2000; 10:211231.MEDLINE
  • 80
    Pontisso P, Morsica G, Ruvoletto MG, Barzon M, Perilongo G, Basso G, Cecchetto G, et al. Latent hepatitis B virus infection in childhood hepatocellular carcinoma. Cancer 1992; 69:27312735.MEDLINE
  • 81
    Yu MC, Yuan JM, Ross RK, Govindarajan S. Presence of antibodies to the hepatitis B surface antigen associated with an excess risk for hepatocellular carcinoma among non-Asians in Los Angeles County, California. Hepatology 1997; 25:226228.MEDLINE
  • 82
    Adachi H, Kaneko S, Matsushita E, Inagaki Y, Unoura M, Kobayashi K. Clearance of HBsAg in seven patients with chronic hepatitis B. Hepatology 1992; 16:13341337.MEDLINE
  • 83
    Chung HT, Lai CL, Lok AS. Pathogenic role of hepatitis B virus in hepatitis B surface antigen-negative decompensated cirrhosis. Hepatology 1995; 22:2529.MEDLINE
  • 84
    Huo T, Wu J, Lee P, Chau G, Lui W, Tsay S, Ting L, et al. Sero-clearance of hepatitis B surface antigen in chronic carriers does not necessarily imply a good prognosis. Hepatology 1998; 28:231236.MEDLINE
  • 85
    Pontisso P, Ruvoletto MG, Fattovich G, Chemello L, Gallorini A, Ruol A, Alberti A. Clinical and virological profiles in patients with multiple hepatitis virus infections. Gastroenterology 1993; 105:15291533.MEDLINE
  • 86
    Ohkawa K, Hayashi N, Yuki N, Masuzawa M, Kato M, Yamamoto K, Hosotsubo H, et al. Long-term follow-up of hepatitis B virus and hepatitis C virus replicative levels in chronic hepatitis patients coinfected with both viruses. J Med Virol 1995; 46:258264.MEDLINE
  • 87
    Zarski JP, Bohn B, Bastie A, Pawlotsky JM, Baud M, Bost-Bezeaux F, Tran van Nhieu J, et al. Characteristics of patients with dual infection by hepatitis B and C viruses. J Hepatol 1998; 28:2733.MEDLINE
  • 88
    Thiers V, Pol S, Persico T, Carnot F, Zylberberg H, Berthelot P, Brechot C, et al. Hepatitis G virus infection in hepatitis C virus-positive patients co-infected or not with hepatitis B virus and/or human immunodeficiency virus. J Viral Hepat 1998; 5:123130.MEDLINE
  • 89
    Sagnelli E, Coppola N, Scolastico C, Filippini P, Santantonio T, Stroffolini T, Piccinino F. Virologic and clinical expressions of reciprocal inhibitory effect of hepatitis B, C, and delta viruses in patients with chronic hepatitis. Hepatology 2000; 32:11061110.MEDLINE
  • 90
    Villa E, Grottola A, Buttafoco P, Trande P, Merighi A, Fratti N, Seium Y, et al. Evidence for hepatitis B virus infection in patients with chronic hepatitis C with and without serological markers of hepatitis B. Dig Dis Sci 1995; 40:813.MEDLINE
  • 91
    Cacciola I, Pollicino T, Squadrito G, Cerenzia G, Orlando ME, Raimondo G. Occult hepatitis B virus infection in patients with chronic hepatitis C liver disease. N Engl J Med 1999; 341:2226.MEDLINE
  • 92
    Bonino F, group II-ahcs. Effect of interferon-α on progression of cirrhosis to hepatocellular carcinoma: a retrospective cohort study. Lancet 1998; 351:15351539.MEDLINE
  • 93
    Zignego A, Fontana R, Puliti S, Barbagli S, Monti M, Careccia G, Giannelli F, et al. Impaired response to alpha interferon in patients with an inapparent hepatitis B and hepatitis C virus coinfection. Arch Virol 1997; 142:535544.MEDLINE
  • 94
    Tagger A, Donato F, Ribero ML, Chiesa R, Portera G, Gelatti U, Albertini A, et al. Case-control study on hepatitis C virus (HCV) as a risk factor for hepatocellular carcinoma: the role of HCV genotypes and the synergism with hepatitis B virus and alcohol. Brescia HCC Study. Int J Cancer 1999; 81:695699.MEDLINE
  • 95
    Shibata Y, Nakata K, Tsuruta S, Hamasaki K, Hayashida Y, Kato Y, Nakao K, et al. Detection of hepatitis B virus X-region DNA in liver tissue from patients with hepatitis C virus-associated cirrhosis who subsequently developed hepatocellular carcinoma. Int J Oncol 1999; 14:11531156.MEDLINE