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Restoration of cerebral blood flow autoregulation and reactivity to carbon dioxide in acute liver failure by moderate hypothermia
Article first published online: 30 DEC 2003
DOI: 10.1053/jhep.2001.25386
Copyright © 2001 American Association for the Study of Liver Diseases
1527-3350/asset/cover.gif?v=1&s=3cd983af6575c8dbfd6b47a63ffa95415ace15f8 "Hepatology")
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How to Cite
Jalan, R., Olde Damink, S. W. M., Deutz, N. E. P., Hayes, P. C. and Lee, A. (2001), Restoration of cerebral blood flow autoregulation and reactivity to carbon dioxide in acute liver failure by moderate hypothermia. Hepatology, 34: 50–54. doi: 10.1053/jhep.2001.25386
Publication History
- Issue published online: 30 DEC 2003
- Article first published online: 30 DEC 2003
- Manuscript Accepted: 13 APR 2001
- Manuscript Received: 11 DEC 2000
References
- 1, , , . Early indicators of prognosis in fulminant hepatic failure. Gastroenterology 1989; 97:439–445.MEDLINE
- 2
- 3
- 4, , , , . Treatment of uncontrolled intracranial hypertension in acute liver failure with moderate hypothermia. Lancet 1999; 354:1164–1168.MEDLINE
- 5
- 6. Normal average value of cerebral blood flow in younger adults is 50 mL/100 g/min. J Cereb Blood Flow Metab 1985; 5:347–349.MEDLINE
- 7, , , , , . Liver function, cerebral blood flow autoregulation, and hepatic encephalopathy in fulminant hepatic failure. Hepatology 1997; 25:837–839.MEDLINE
- 8, . Pathophysiology of cerebral edema in fulminant hepatic failure. J Hepatol 1999; 31:771–776.MEDLINE
- 9, , , , , , . Cerebral hemodynamic and metabolic changes in fulminant hepatic failure: a retrospective study. Hepatology 1994; 19:80–87.MEDLINE
- 10, . Experimental acute hepatic encephalopathy: relationship of pathological cerebral vasodilatation to increased intracranial pressure. Neurosurgery 1982; 10:737–741.MEDLINE
- 11, , , , , , . Dissociated cerebral vasoparalysis in acute liver failure. A hypothesis of gradual cerebral hyperaemia. J Hepatol 1996; 25:145–151.MEDLINE
- 12, , , . Cerebral blood flow and metabolism in fulminant liver failure. Hepatology 1994; 19:1407–1413.MEDLINE
- 13, , , Mild hypothermia modifies ammonia-induced brain edema in rats after portacaval anastomosis. Gastroenterology 1999; 116:686–693.MEDLINE
- 14, . Neuronal nitric oxide synthase and hepatic encephalopathy. Metab Brain Dis 1998; 13:175–189.MEDLINE
- 15, , Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis. Hepatology 1999; 30:876–880.MEDLINE
- 16, , , , , Regional cerebral blood flow during mechanical hyperventilation in patients with fulminant hepatic failure. Hepatology 1999; 30:1368–1373.MEDLINE
- 17, . The nitrous oxide method for the quantitative determination of cerebral blood flow in man: theory, procedure and normal values. J Clin Invest 1947; 27:476–483.
- 18, . The cerebral blood flow in male subjects as measured by the nitrous oxide technique, normal values for blood flow, oxygen utilization, glucose utilization and peripheral resistance with observations on the effect of tilting and anxiety. J Appl Physiol 1949; 28:1163–1171.
- 19, , , . Cerebral blood flow and metabolism in patients with chronic liver disease undergoing orthotopic liver transplantation. Hepatology 1998; 27:369–376.MEDLINE
- 20, , , . Regional cerebral blood flow autoregulation in patients with fulminant hepatic failure. Liver Transplantation 2000; 6:795–800.MEDLINE
- 21
- 22, , , , . Loss of cerebrovascular autoregulation in experimental meningitis in rabbits. J Clin Invest 1990; 85:577–581.MEDLINE
- 23, , , , , . Hepatectomy corrects cerebral hyperperfusion in fulminant hepatic failure. Transplant Proc 1994; 26:1794–1795.MEDLINE
- 24, , , , . Total hepatectomy and liver transplantation as two-stage procedure. Ann Surg 1993; 218:3–9.MEDLINE
- 25, , , . Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats. Am J Physiol 1991; 261:H825–H829.MEDLINE
- 26, , , , . Restoration of cerebrovascular CO2 responsivity by glutamine synthesis inhibition in hyperammonemic rats. Circ Res 1992; 71:1220–1230.MEDLINE
- 27, , , , , . Mild hypothermia delays the onset of coma and prevents brain edema and extracellular brain glutamate accumulation in rats with acute liver failure. Hepatology 2000; 31:872–877.MEDLINE
- 28, , , , . Effects of mild hypothermia on the cortical release of excitatory amino acids and nitric oxide synthesis following hypoxia. J Neurotrauma 1999; 16:1083–1093.MEDLINE
- 29, . Pathophysiology of hypotension in patients with fulminant hepatic failure. Gut 1977; 18:1021–1026.MEDLINE
- 30, , , , , , . Hepatic blood flow and metabolism in patients with fulminant hepatic failure before and after high volume plasmapheresis. Hepatology 1999; 29:347–355.MEDLINE
- 31, , Impaired pressor reactivity in cirrhosis: evidence for a peripheral vascular defect. Hepatology 1991; 13:689–694.MEDLINE
- 32, , , , . Role of angiotensin II in regulation of basal and sympathetically stimulated vascular tone in early and advanced cirrhosis. Gastroenterology 2000; 118:565–572.MEDLINE