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Is “Gilbert's” the culprit in indinavir-induced hyperbilirubinemia?
Article first published online: 30 DEC 2003
DOI: 10.1053/jhep.2002.0351269
Copyright © 2002 American Association for the Study of Liver Diseases
Additional Information
How to Cite
Sen, S. and Jalan, R. (2002), Is “Gilbert's” the culprit in indinavir-induced hyperbilirubinemia?. Hepatology, 35: 1269–1270. doi: 10.1053/jhep.2002.0351269
Publication History
- Issue published online: 30 DEC 2003
- Article first published online: 30 DEC 2003
References
- 1
- 2, , , , , , , et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. N Engl J Med 1997; 337:725–733. MEDLINE
- 3, , , . HIV protease inhibitors: advances in therapy and adverse reactions, including metabolic complications. Pharmacotherapy 1999; 19:281–298. MEDLINE
- 4, , , , , , . Disposition of indinavir, a potent HIV-1 protease inhibitor, after an oral dose in humans. Drug Metab Dispos 1996; 24:1389–1394. MEDLINE
- 5
- 6, , , , , , , et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 1995; 333:1171–1175. MEDLINE
- 7, , , . Association of human liver bilirubin UDP-glucuronosyltransferase activity with a polymorphism in the promoter region of the UGT1A1 gene. J Hepatol 2000; 33:348–351. MEDLINE
- 8, , , , , . Bile pigments as HIV-1 protease inhibitors and their effects on HIV-1 viral maturation and infectivity in vitro. Biochem J 1996; 320:681–686. MEDLINE
- 9, , , , , , , et al. The absence of hyperbilirubinaemia is highly predictive of treatment failure in advanced HIV-infected patients treated with indinavir. Int J STD AIDS 2001; 12:29–33. MEDLINE

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