• 1
    Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation. FASEB J 1996; 10:267282. MEDLINE
  • 2
    Costa RH, Holterman A-X, Rausa FM, Adami G. Gene regulation and in vivo function of liver transcription factors. In: AriasIM, BoyerJL, ChisariFV, FaustoN, SchachterD, ShafritzD, (eds): The Liver: Biology and Pathobiology (4th ed). Philadelphia, PA: Lippincott Williams & Wilkins; 2001, pp 5975.
  • 3
    Lemaigre FP, Durviaux SM, Truong O, Lannoy VJ, Hsuan JJ, Rousseau GG. Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domain. Proc Natl Acad Sci U S A 1996; 93:94609464. MEDLINE
  • 4
    Samadani U, Costa RH. The transcriptional activator hepatocyte nuclear factor six regulates liver gene expression. Mol Cell Biol 1996; 16:62736284. MEDLINE
  • 5
    Rausa F, Samadani U, Ye H, Lim L, Fletcher CF, Jenkins NA, Copeland NG, et al. The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3β in the developing murine liver and pancreas. Dev Biol 1997; 192:228246. MEDLINE
  • 6
    Lannoy VJ, Rodolosse A, Pierreux CE, Rousseau GG, Lemaigre FP. Transcriptional stimulation by hepatocyte nuclear factor-6. Target-specific recruitment of either CREB-binding protein (CBP) or p300/CBP-associated factor (p/CAF). J Biol Chem 2000; 275:2209822103. MEDLINE
  • 7
    Tan Y, Adami G, Costa RH. Maintaining HNF-6 expression prevents AdHNF3β mediated decrease in hepatic levels of Glut2 and glycogen. Hepatology 2002; 35:790798. MEDLINE
  • 8
    Landry C, Clotman F, Hioki T, Oda H, Picard JJ, Lemaigre FP, Rousseau GG. HNF-6 is expressed in endoderm derivatives and nervous system of the mouse embryo and participates to the cross-regulatory network of liver-enriched transcription factors. Dev Biol 1997; 192:247257. MEDLINE
  • 9
    Jacquemin P, Durviaux SM, Jensen J, Godfraind C, Gradwohl G, Guillemot F, Madsen OD, et al. Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3. Mol Cell Biol 2000; 20:44454454. MEDLINE
  • 10
    Tan Y, Hughes DE, Wang X, Costa RH. Adenovirus-mediated hepatic increase in HNF 3β or HNF-3α shows differences in levels of liver glycogen and gene expression. Hepatology 2002; 35:3039. MEDLINE
  • 11
    Zhou L, Lim L, Costa RH, Whitsett JA. Thyroid transcription factor-1, hepatocyte nuclear factor-3β, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J Histochem Cytochem 1996; 44:11831193. MEDLINE
  • 12
    Rausa FM, Tan Y, Zhou H, Yoo K, Stolz DB, Watkins S, Franks RR, et al. Elevated levels of HNF-3β in mouse hepatocytes influence expression of genes involved in bile acid and glucose homeostasis. Mol Cell Biol 2000; 20:82648282. MEDLINE
  • 13
    Rausa FM, Ye H, Lim L, Duncan SA, Costa RH. In situ hybridization with 33P-labeled RNA probes for determination of cellular expression patterns of liver transcription factors in mouse embryos. Methods: A Companion to Methods in Enzymology 1998; 16:2941. MEDLINE
  • 14
    Samadani U, Qian X, Costa RH. Identification of a transthyretin enhancer sequence that selectively binds the hepatocyte nuclear factor-3β isoform. Gene Expr 1996; 6:2333. MEDLINE
  • 15
    Nag A, Datta A, Yoo K, Bhattacharyya D, Chakrabortty A, Wang X, Slagle BL, et al. DDB2 induces nuclear accumulation of the hepatitis B virus X protein independently of binding to DDB1. J Virol 2001; 75:1038310392. MEDLINE
  • 16
    Liu Z, Sakamoto T, Ezure T, Yokomuro S, Murase N, Michalopoulos G, Demetris AJ. Interleukin-6, hepatocyte growth factor, and their receptors in BEC during a type I ductular reaction in mice: interactions between the periductal inflammatory and stromal cells and the biliary epithelium. Hepatology 1998; 28:12601268. MEDLINE
  • 17
    Polimeno L, Azzarone A, Zeng QH, Panella C, Subbotin B, Carr B, Bouzahzah B, et al. Cell proliferation and oncogene expression after bile duct ligation in the rat: evidence of a specific growth effect on bile duct cells. Hepatology 1995; 21:10701078. MEDLINE
  • 18
    Bisgaard HC, Nagy P, Santori-Rugiu E, Thorgeirsson SS. Proliferation, apoptosis and induction of hepatic transcription factors are characteristics of the early response of biliary epithelial (oval) cells to chemical carcinogens. Hepatology 1996; 23:6270. MEDLINE
  • 19
    Green RM, Gollan JL, Hagenbuch B, Meier PJ, Beier DR. Regulation of hepatocyte bile salt transporters during hepatic regeneration. Am J Physiol 1997; 273:G621G627. MEDLINE
  • 20
    Nakano K, Chijiiwa K, Okamoto S, Yamashita H, Kuroki S, Tanaka M. Hepatic cholesterol 7α-hydroxylase activity and serum 7α-hydroxy-cholesterol level during liver regeneration after partial hepatectomy in rats. Eur Surg Res 1995; 27:389395. MEDLINE
  • 21
    Gartung C, Ananthanarayanan M, Rahman MA, Schuele S, Nundy S, Soroka CJ, Stolz A, et al. Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis. Gastroenterology 1996; 110:199209. MEDLINE
  • 22
    Zoltowska M, Delvin EE, Paradis K, Seidman E, Levy E. Bile duct cells: a novel in vitro model for the study of lipid metabolism and bile acid production. Am J Physiol 1999; 276:G407G414. MEDLINE
  • 23
    Baer HU, Friess H, Abou-Shady M, Berberat P, Zimmermann A, Gold LI, Korc M, et al. Transforming growth factor betas and their receptors in human liver cirrhosis. Eur J Gastroenterol Hepatol 1998; 10:10311039. MEDLINE
  • 24
    Abdel-Aziz G, Rescan P, Clement B, Lebeau G, Rissel M, Grimaud J, Campion J, et al. Cellular sources of matrix proteins in experimentally induced cholestatic rat liver. J Pathol 1991; 164:167174. MEDLINE
  • 25
    Desmouliere A, Darby I, Costa A, Raccurt M, Tuchweber B, Sommer P, Gabbiani G. Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat. Lab Invest 1997; 76:765778. MEDLINE
  • 26
    Milani S, Herbst H, Schuppan D, Kim K, Riecken E, Stein H. Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis. Gastroenterology 1990; 98:175184. MEDLINE
  • 27
    Saperstein LA, Jirtle RL, Farouk M, Thompson HJ, Chung KS, Meyers WC. Transforming growth factor-β1 and mannose 6-phosphate/insulin-like growth factor-II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat. Hepatology 1994; 19:412417. MEDLINE
  • 28
    Lahuna O, Fernandez L, Karlsson H, Maiter D, Lemaigre FP, Rousseau GG, Gustafsson J, et al. Expression of hepatocyte nuclear factor 6 in rat liver is sex-dependent and regulated by growth hormone. Proc Natl Acad Sci U S A 1997; 94:1230912313. MEDLINE
  • 29
    Lahuna O, Rastegar M, Maiter D, Thissen JP, Lemaigre FP, Rousseau GG. Involvement of STAT5 (signal transducer and activator of transcription 5) and HNF-4 (hepatocyte nuclear factor 4) in the transcriptional control of the HNF-6 gene by growth hormone. Mol Endocrinol 2000; 14:285294. MEDLINE
  • 30
    Rastegar M, Lemaigre FP, Rousseau GG. Control of gene expression by growth hormone in liver: key role of a network of transcription factors. Mol Cell Endocrinol 2000; 164:14. MEDLINE
  • 31
    Rastegar M, Rousseau GG, Lemaigre FP. CCAAT/enhancer-binding protein-alpha is a component of the growth hormone-regulated network of liver transcription factors. Endocrinology 2000; 141: 16861692 MEDLINE