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References

  • 1
    Theodore D, Fried MW. Natural history and disease manifestations of hepatitis C infection. Curr Top Microbiol Immunol 2000; 242:4354.
  • 2
    Rosenberg S. Recent advances in the molecular biology of hepatitis C virus. J Mol Biol 2001; 313:451464.
  • 3
    Cerny A, Chisari FV. Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence. Hepatology 1999; 30:595601.
  • 4
    Davis GL. Combination treatment with interferon and ribavirin for chronic hepatitis C. Clin Liver Dis 1999; 3:811826.
  • 5
    Poynard T, McHutchison J, Manns M, Trepo C, Lindsay K, Goodman Z, Ling MH, et al. Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C. Gastroenterology 2002; 122:13031313.
  • 6
    Biron CA. Role of early cytokines, including alpha and beta interferons (IFN-α/β), in innate and adaptive immune responses to viral infections. Semin Immunol 1998; 10:383390.
  • 7
    Friedman RL, Manly SP, McMahon M, Kerr IM, Stark GR. Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells. Cell 1984; 38:745755.
  • 8
    Katze MG, He Y, Gale M Jr. Viruses and interferon: a fight for supremacy. Nat Rev Immunol 2002; 2:675687.
  • 9
    Gale M Jr., Blakely CM, Kwieciszewski B, Tan SL, Dossett M, Tang NM, Korth MJ, et al. Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Mol Cell Biol 1998; 18:52085218.
  • 10
    Taylor DR, Shi ST, Romano PR, Barber GN, Lai MM. Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein [Comments]. Science 1999; 285:107110.
  • 11
    Pflugheber J, Fredericksen B, Sumpter R Jr., Wang C, Ware F, Sodora DL, Gale M Jr. Regulation of PKR and IRF-1 during hepatitis C virus RNA replication. Proc Natl Acad Sci U S A 2002; 99:46504655.
  • 12
    Lohmann V, Korner F, Koch J, Herian U, Theilmann L, Bartenschlager R. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 1999; 285:110113.
  • 13
    Blight KJ, Kolykhalov AA, Rice CM. Efficient initiation of HCV RNA replication in cell culture. Science 2000; 290:19721974.
  • 14
    Guo JT, Bichko VV, Seeger C. Effect of alpha interferon on the hepatitis c virus replicon. J Virol 2001; 75:85168523.
  • 15
    Ikeda M, Yi M, Li K, Lemon SM. Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells. J Virol 2002; 76:29973006.
  • 16
    Eisen MB, Spellman PT, Brown PO, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A 1998; 95:1486314868.
  • 17
    Pietschmann T, Lohmann V, Rutter G, Kurpanek K, Bartenschlager R. Characterization of cell lines carrying self-replicating hepatitis C virus RNAs. J Virol 2001; 75:1252264.
  • 18
    Mottola G, Cardinali G, Ceccacci A, Trozzi C, Bartholomew L, Torrisi MR, Pedrazzini E, et al. Hepatitis C virus nonstructural proteins are localized in a modified endoplasmic reticulum of cells expressing viral subgenomic replicons. Virology 2002; 293:3143.
  • 19
    Darnell JE Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264:14151421.
  • 20
    Tian Z, Shen X, Feng H, Gao B. IL-1 β attenuates IFN-α β-induced antiviral activity and STAT1 activation in the liver: involvement of proteasome-dependent pathway. J Immunol 2000; 165:39593965.
  • 21
    Ichikawa T, Nakao K, Nakata K, Yamashita M, Hamasaki K, Shigeno M, Abiru S, et al. Involvement of IL-1β and IL-10 in IFN-α-mediated antiviral gene induction in human hepatoma cells. Biochem Biophys Res Commun 2002; 294:414422.
  • 22
    Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD. How cells respond to interferons. Annu Rev Biochem 1998; 67:227264.
  • 23
    Der SD, Zhou A, Williams BR, Silverman RH. Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays. Proc Natl Acad Sci U S A 1998; 95:1562315628.
  • 24
    de Veer MJ, Holko M, Frevel M, Walker E, Der S, Paranjape JM, Silverman RH, et al. Functional classification of interferon-stimulated genes identified using microarrays. J Leukoc Biol 2001; 69:912920.
  • 25
    Bigger CB, Brasky KM, Lanford RE. DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection. J Virol 2001; 75:70597066.
  • 26
    Lanford RE, Bigger C, Bassett S, Klimpel G. The chimpanzee model of hepatitis C virus infections. Ilar J 2001; 42:117126.
  • 27
    Kelly JM, Porter AC, Chernajovsky Y, Gilbert CS, Stark GR, Kerr IM. Characterization of a human gene inducible by α- and β- interferons and its expression in mouse cells. EMBO J 1986; 5:16011606.
  • 28
    Clauss IM, Wathelet MG, Szpirer J, Content J, Islam MQ, Levan G, Szpirer C, et al. Chromosomal localization of two human genes inducible by interferons, double-stranded RNA, and viruses. Cytogenet Cell Genet 1990; 53:166168.
  • 29
    Porter AC, Chernajovsky Y, Dale TC, Gilbert CS, Stark GR, Kerr IM. Interferon response element of the human gene 6-16. EMBO J 1988; 7:8592.
  • 30
    Nguyen VA, Chen J, Hong F, Ishac EJ, Gao B. Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential regulation by acute ethanol via a protein kinase C-dependent mechanism. Biochem J 2000; 349:427434.
  • 31
    Radaeva S, Jaruga B, Hong F, Kim WH, Fan S, Cai H, Strom S, et al. Interferon-α activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes. Gastroenterology 2002; 122:10201034.
  • 32
    Yang CH, Murti A, Pfeffer SR, Kim JG, Donner DB, Pfeffer LM. Interferon α/β promotes cell survival by activating nuclear factor κ B through phosphatidylinositol 3-kinase and Akt. J Biol Chem 2001; 276:1375613761.
  • 33
    Yang CH, Shi W, Basu L, Murti A, Constantinescu SN, Blatt L, Croze E, et al. Direct association of STAT3 with the IFNAR-1 chain of the human type I interferon receptor. J Biol Chem 1996; 271:80578061.
  • 34
    Yang CH, Murti A, Pfeffer LM. STAT3 complements defects in an interferon-resistant cell line: evidence for an essential role for STAT3 in interferon signaling and biological activities. Proc Natl Acad Sci U S A 1998; 95:55685572.
  • 35
    Gong G, Waris G, Tanveer R, Siddiqui A. Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-κ B. Proc Natl Acad Sci U S A 2001; 98:95999604.
  • 36
    Fredericksen B, Akkaraju GR, Foy E, Wang C, Pflugheber J, Chen ZJ, Gale M Jr. Activation of the interferon-β promoter during hepatitis C virus RNA replication. Viral Immunol 2002; 15:2940.