• 1
    Mas A, Rodes J. Acute hepatic failure. Lancet 1997; 349:10811085.
  • 2
    Hoofnagle JH, Carithers RL, Shapiro C, Ascher N. Fulminant hepatic failure: summary of a workshop. Hepatology 1995; 21:240252.
  • 3
    Rolando N, Wade J, Davalos M, Wendon J, Philpott-Howard J, Williams R. The systemic inflammatory response syndrome in acute liver failure. Hepatology 2000; 32:734739.
  • 4
    Bihari DJ, Gimson AES, Williams R. Cardiovascular, pulmonary and renal complications of acute hepatic failure. Semin Liver Dis 1986; 2:119128.
  • 5
    Lee WM. Acute liver failure. N Engl J Med 1993;18621872.
  • 6
    Krowka MJ, Cortese DA. Pulmonary aspects of liver disease and liver transplantation. Clin Chest Med 1989; 10:593616.
  • 7
    Trewby PN, Warren R, Contini S, Crosbie WA, Wilkinson SP, Laws JW, Williams R. Incidence and pathophysiology of pulmonary edema in fulminant hepatic failure. Gastroenterology 1978; 74:859865.
  • 8
    Baudouin SV, Howdle P, O'Grady JG, Webster NR. Acute lung injury in acute hepatic failure following paracetamol poisoning. Thorax 1995; 50:399402.
  • 9
    Matuschak GM. Liver-lung interaction in critical illness. In: PinskyMR, DrainautJF, ArtigasA, eds. The Splanchnic Circulation, No Longer a Silent Partner. Update in Intensive Care and Emergency Medicine. Berlin, Heidelberg, New York: Springer-Verlag 1995;23:7393
  • 10
    Pittet F, Mackersie RC, Martin TR, Matthay MA. Biological markers of acute lung injury: prognostic and pathogenetic significance. Am J Respir Crit Care Med 1997; 155:11871205.
  • 11
    Gregory T, Longmore W, Moxley M, Whitsett JA, Reed CR, Fowler AA III, Hudson LD, et al. Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome. J Clin Invest 1991; 65:19761981.
  • 12
    Nakos G, Kitsiouli EI, Tsangaris I, Lekka ME. Bronchoalveolar lavage fluid characteristics of early, intermediate and late phases of ARDS. Intensive Care Med 1998; 24:296303.
  • 13
    Hite RD, Seeds MC, Jacinto RB, Balasubramanian R, Waite M, Bass D. Hydrolysis of surfactant-associated phosphatidylcholine by mammalian secretory phospholipase A2. Am J Physiol 1998; 275:L740L747.
  • 14
    Holm BA, Keicher L, Liu MY, Sokolowski J, Enhorning G. Inhibition of pulmonary surfactant function by phospholipases. J Appl Physiol 1991; 71:317321.
  • 15
    Tarbet EB, Stafforini DM, Elstad MR, Zimmerman GA, McIntyre TM, Prescott SM. Liver cells secrete the plasma form of platelet-activating factor acetylhydrolase. J Biol Chem 1991; 266:1666716673.
  • 16
    Hanid MA, Mackenzie RL, Jenner RE, Chase RA, Mellon PJ, Trewby PN, Janota I, et al. Intracranial pressure in pigs with surgically induced acute liver failure. Gastroenterology 1978; 76:123131.
  • 17
    Arkadopoulos N, Chen S, Khalili TM, Detry O, Hewitt WR, Lilja H, Kamachi H, et al. Transplantation of hepatocytes for prevention of intracranial hypertension in pigs with ischemic liver failure. Cell Transplant 1998; 7:357363.
  • 18
    Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193:265275.
  • 19
    Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37:911917.
  • 20
    Bartlett GR. Phosphorus assay in column chromatography. J Biol Chem 1959; 234:466468.
  • 21
    Kitsiouli EI, Nakos G, Lekka ME. Differential determination of phospholipase A2 and PAF-acetylhydrolase in biological fluids using fluorescent substrates. J Lipid Res 1999; 40:23462356.
  • 22
    Pearce ML, Yamashita J, Beazell J. Measurement of pulmonary edema. Circ Res 1965; 16:482488.
  • 23
    Lucke B. The fulminant form of epidemic hepatitis. Am J Pathol 1946; 22:867945.
  • 24
    Ellis A, Wendon J. Circulatory, respiratory, cerebral and renal derangements in acute liver failure: pathophysiology and management. Semin Liver Dis 1996; 16:379388.
  • 25
    Colletti LM, Burtch GD, Remick DG, Kunkel SL, Strieter RM, Guice KS, Oldham KT, et al. The production of tumor necrosis factor α and the development of a pulmonary capillary injury following hepatic ischemia-reperfusion. Transplantation 1990; 49:268272.
  • 26
    Frenandez L, Heredia N, Grande L, Gomez G, Rimola A, Marco A, Gelpi E, et al. Preconditioning protect liver and lung damage in rat liver transplantation: the role of xanthine/xantine oxidase. Hepatology 2002; 36:562572.
  • 27
    Walsh TS, McLellan S, Mackenzie SJ, Lee A. Hyperlactatemia and pulmonary lactate production in patients with fulminant hepatic failure. Chest 1999; 116:471476.
  • 28
    Routsi C, Bardouniotou H, Delivaria-Ioannidou V, Kazi D, Roussos C, Zakyntinos S. Pulmonary lactate release in patients with acute lung injury is not attributable to lung hypoxia. Crit Care Med 1999; 27:24692473.
  • 29
    Desille M, Mahler S, Seguin P, Malledant Y, Fremond B, Sebille V, Bouix A, et al. Reduced encephalopathy in pigs with ischemia-induced acute hepatic failure treated with bioartificial liver containing alginate-entrapped hepatocytes. Crit Care Med 2002; 30:658663.
  • 30
    Theodoraki K, Kostopanagiotou G, Smyrniotis V, Arkadopoulos N, Prachalias A, Pyrsopoulos N, Papadimitriou J. Haemodynamic changes in ischaemic vs. anhepatic pig experimental model of acute liver failure. Eur J Anaesthesiol 2002; 19:4046.
  • 31
    Von Wichert P, Joseph K, Muller B, Frank WM. Bronchoalveolar lavage. Quantification of intraalveolar fluid. Am Rev Respir Dis 1993; 147:148152.
  • 32
    Arbibe L, Koumanov K, Vial D, Rougeot C, Faure G, Havet N, Longacre S, et al. Generation of lyso-phospholipids from surfactant in acute lung injury is mediated by type-II phospholipase A2 and inhibited by a direct surfactant protein A-phospholipase A2 protein interaction. J Clin Invest 1998; 102:11521160.
  • 33
    Hamm H, Kroegel C, Hohlfeld J. Surfactant: a review of its functions and relevance in adult respiratory disorders. Respir Med 1996; 90:251270.
  • 34
    Matsumoto K, Taki F, Kondoh Y, Taniguchi H, Tagaki K. Platelet activating factor in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome. Clin Exp Pharmacol Physiol 1992; 19:509515.
  • 35
    Kim DK, Fukuda T, Thompson BT, Cockrill B, Hales C, Bonventre JV. Bronchoalveolar lavage fluid phospholipase A2 activities are increased in human adult respiratory distress syndrome. Am J Physiol 1995; 269:L109L118.
  • 36
    Arbibe L, Vial D, Rosinski-Chupin I, Havet N, Huerre M, Vargaftig BB, Touqui L. Endotoxin induces expression of type II phospholipase A2 in macrophages during acute lung injury in guinea pigs: involvement of TNF-α in lipopolysaccharide-induced type II phospholipase A2 synthesis. J Immunol 1997; 159:391400.
  • 37
    Nevalainen TJ, Haapamaki MM, Gronroos JM. Roles of phospholipases A2 in inflammatory diseases and trauma. Biochim Biophys Acta 2000; 1488:8390.
  • 38
    Tjoelker LW, Wilder C, Eberhardt C, Stafforini DM, Dietsch G, Schimpf B, Hooper S, et al. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature 1995; 374:549553.
  • 39
    Evans TW, Chung KF, Rogers DF, Barnes PJ. Effect of platelet-activating factor on airway vascular permeability: possible mechanism. J Appl Physiol 1987; 63:479484.
  • 40
    Sakai A, Chang S, Voelkel NF. Importance of vasoconstriction in lipid mediator-induced pulmonary edema. J Appl Physiol 1989; 66:26672674.
  • 41
    Veldhuizen RA, Tremblay LN, Govindarajan A,van Rozendaal BA, Haagsman HP, Slutsky AS. Pulmonary surfactant is altered during mechanical ventilation of isolated rat lung. Crit Care Med 2000; 28:25452551.
  • 42
    Wright JR, Dodds LG. Regulation of pulmonary surfactant secretion and clearance. Annu Rev Physiol 1991; 53:395414.
  • 43
    Oyarzun MJ, Clements JA. Control of lung surfactant by ventilation, adrenergic mediators and prostaglandins in the rabbit. Am Rev Respir Dis 1978; 117:879891.
  • 44
    Kikkawa Y, Smith F. Cellular and biochemical aspects of pulmonary surfactant in health and disease. Lab Invest 1983; 49:122139.
  • 45
    Smith WS, Matthay MA. Evidence for a hydrostatic mechanism in human neurogenic pulmonary edema. Chest 1997; 111:13261333.
  • 46
    Dreyfuss D, Saumon G. Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 1998; 157:294323.
  • 47
    Ede RJ, Gimson AE, Bihari D, Williams R. Control hyperventilation in the prevention of cerebral oedema in fulminant hepatic failure. J Hepatol 1986; 2:4351.