Session I: Controversies in Hepatobiliary Malignancy
Surgery and transplantation for hepatocellular cancer
Article first published online: 30 DEC 2003
Copyright © 2000 American Association for the Study of Liver Diseases
Supplement: Advances and Controversies in Liver Transplantation
Volume 6, Issue Supplement 6B, pages s16–s22, November 2000
How to Cite
Wall, W. J. and Marotta, P. J. (2000), Surgery and transplantation for hepatocellular cancer. Liver Transpl, 6: s16–s22. doi: 10.1053/jlts.2000.19010
- Issue published online: 30 DEC 2003
- Article first published online: 30 DEC 2003
1. Curative treatment of hepatocellular carcinoma (HCC) depends on early diagnosis.
2. The cure rate for operable HCC occurring in the absence of cirrhosis is only 10% to 25%.
3. Features of HCC in patients with cirrhosis that are associated with a 5-year survival rate of 75% after liver transplantation include (1) solitary tumor less than 5 cm; (2) 3 or fewer tumors, each less than 3 cm; and (3) absence of vascular invasion.
4. Advanced cirrhosis limits the widespread application of partial hepatectomy to patients with HCC.
5. Neoadjuvant therapy has not yet been proven to improve patient outcome for early-stage HCC that is promptly treated by transplantation.