Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation

Authors

  • Chung-Mau Lo,

    Corresponding author
    1. Department of Surgery, and Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Hong Kong
    • Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Rd, Hong Kong. Telephone: 852-2855-4761; FAX: 852-2817-5475
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  • Chi-Leung Liu,

    1. Department of Surgery, and Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Hong Kong
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  • Sheung-Tat Fan

    1. Department of Surgery, and Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Hong Kong
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Abstract

Dysfunction of a small-for-size graft is an important clinical problem after living donor liver transplantation in adults. We report a case of primary nonfunction after a small-for-size right lobe living donor liver transplant that was successfully salvaged by reduction of portal pressure and blood flow after splenic artery ligation. The case established portal hyperperfusion injury as a cause of primary nonfunction in a small-for-size graft and we recommend that portal pressure be measured when clinical suspicion arises. Splenic artery ligation is a technically simple procedure that can be applied for the prevention or treatment of such injury

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