Hypothermia in the resuscitation of the neonate: A glance in my rear-view mirror
Article first published online: 29 MAR 2007
Volume 95, Issue 10, pages 1172–1174, October 2006
How to Cite
Westin, B. (2006), Hypothermia in the resuscitation of the neonate: A glance in my rear-view mirror. Acta Paediatrica, 95: 1172–1174. doi: 10.1080/08035250600794583
- Issue published online: 29 MAR 2007
- Article first published online: 29 MAR 2007
Recent research indicates that the outcome of perinatal hypoxia-ischaemia can be improved by hypothermia. This was actually first observed about 40 years ago, as discussed in this article. Clinical application of whole-body hypothermia in the asphyxiated neonate showed a positive effect. Reference is made to previous review articles on the subject. A large experimental study indicated that the degree of protection against hypoxic-ischaemic damage, as judged by the conditioned avoidance response, was dependent on the fall in body temperature. The earlier reported resistance against hypothermia in the asphyxiated neonate is discussed and analysed.
Conclusion: Experimental and clinical evidence suggest that hypothermia may be of value in resuscitation of the neonate.