Cognitive Impairment in Individuals Currently Using Methamphetamine

Authors

  • Sara L. Simon Ph.D.,

    Corresponding author
    1. From the VA Medications Development Research Unit, Long Beach, Calif.
    2. The Los Angeles Addiction Research Consortium
    Search for more papers by this author
  • Catherine Domier B.A.,

    1. From the VA Medications Development Research Unit, Long Beach, Calif.
    2. The Los Angeles Addiction Research Consortium
    Search for more papers by this author
  • Jennifer Carnell B.S.,

    1. From the VA Medications Development Research Unit, Long Beach, Calif.
    2. The Los Angeles Addiction Research Consortium
    Search for more papers by this author
  • Paul Brethen MFCC,

    1. The Matrix Institute on Addictions, Los Angeles, Calif.
    2. The Los Angeles Addiction Research Consortium
    Search for more papers by this author
  • Richard Rawson Ph.D.,

    1. From the VA Medications Development Research Unit, Long Beach, Calif.
    2. The Matrix Institute on Addictions, Los Angeles, Calif.
    3. The Los Angeles Addiction Research Consortium
    Search for more papers by this author
  • Walter Ling M.D.

    1. From the VA Medications Development Research Unit, Long Beach, Calif.
    2. The Matrix Institute on Addictions, Los Angeles, Calif.
    3. The Los Angeles Addiction Research Consortium
    Search for more papers by this author

Address correspondence to Dr. Simon, Los Angeles Addiction Research Consortium, 9375 Archibald Ave., Suite 102, Rancho Cucamonga, CA 91730. E-mail: slsimonucla.edu.

Abstract

Although there are increasing reports of methamphetamine use, studies examining the cognitive consequences of methamphetamine have not been performed on a population currently using the drug. To characterize this population, 65 people currently using MA regularly and 65 non-users were given a battery of cognitive tests. The battery included recall, recognition, Digit Symbol, Trail Making A & B, Stroop, Wisconsin Card Sort, backward digit span, and the FAS test of verbal fluency. The methamphetamine users were significantly more impaired on recall tasks, digit symbol, Stroop color words, and Trail Making B, but scores fell within the normal ranges on the other measures.

Ancillary