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Article
Evidence for antiradical and antioxidant properties of four biologically active N,N-Diethylaminoethyl ethers of flavaone oximes: A comparison with natural polyphenolic flavonoid rutin action
Article first published online: 17 JAN 2008
DOI: 10.1080/15216549700202141
Copyright © 1997 International Union of Biochemistry and Molecular Biology
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How to Cite
Metodiewa, D., Kochman, A. and Karolczak, S. (1997), Evidence for antiradical and antioxidant properties of four biologically active N,N-Diethylaminoethyl ethers of flavaone oximes: A comparison with natural polyphenolic flavonoid rutin action. IUBMB Life, 41: 1067–1075. doi: 10.1080/15216549700202141
Publication History
- Issue published online: 17 JAN 2008
- Article first published online: 17 JAN 2008
- Abstract
- Cited By
Abstract
The antiradical and antioxidant activities of four biologically active N,N-diethyloaminoethyl ethers of flavanone oximes (N,N-DEAEFo) were investigated in vitro and compared with these of polyphenolic flavonoid (rutin). Four experimental models were used: iron- and ascorbate driven Fenton systems, γ-radiolysis, xanthine/xanthine oxidase system and diphenylpicrylhydrazyl (DPPH) radical scavenging. The results clearly indicate that N,N-DEAEFo are acting as promising antioxidants and radioprotectors comparable to rutin activities: they should prove to be useful under acute oxidative stress conditions for which both properties were required.