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  • Borrello MG et al. (1996) The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cγ. Mol Cell Biol, 16, 21512163.
  • Cohen T, Gitay-Goren H, Neufeld G and Levi B-Z (1992) High levels of biologically active vascular endothelial growth factor (VEGF) are produced by the baculovirus expression system. Growth Factors, 7, 131138.
  • Connolly DT, Heuvelman DM, Nelson R, Olander JV, Eppley BL, Delfino JJ, Siegel NR, Leimgruber RM and Feder J (1989) Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest, 84, 14701478.
  • Cunningham SA, Arrate MP, Brock TA and Waxham MN (1997) Interaction of Flt-1 and KDR with phospholipase C-γ: identification of the phosphotyrosine binding sites. Biochem Biophys Res Commun, 240, 635639.
  • de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N and Williams LT (1992) The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science, 255, 989991.
  • Dougher-Vermazen M, Hulmes JD, Bohlen P and Terman BI (1994) Biological activity and phosphorylation sites of the bacterially expressed cytosolic domain of the KDR VEGF-receptor. Biochem Biophys Res Commun, 205, 728738.
  • Fanti WJ, Escobedo JA, Martin GA, Turck CW, Del Rosario M, McCormick F and Williams LT (1992) Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell, 69, 413423.
  • Ferrara N and Henzel WJ (1989) Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun, 161, 851858.
  • Ferrara N, Houck KA, Jakeman LB, Winer J and Leung DW (1991) The vascular endothelial growth factor family of polypeptides. J Cell Biochem, 47, 211218.
  • Folkman J (1990) What is the evidence that tumors are angiogenesis-dependent? J Natl Cancer Inst, 82, 46.
  • Fong G-H, Rossant J, Gertsenstein M and Breitman ML (1995) Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature, 376, 6670.
  • Fujio Y and Walsh K (1999) Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J Biol Chem, 274, 1634916354.
  • Igarashi K, Shigeta K, Isohara T, Yamano T and Uno I (1998) Sck interacts with KDR and Flt-1 via its SH2 domain. Biochem Biophys Res Commun, 251, 7782.
  • Keck PJ, Hauser SD, Krivi G, Sanzo K, Warren T, Feder J and Connolly DT (1989) Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science, 246, 13091312.
  • Leung DW, Cachianes G, Kuang W-J, Goeddel DV and Ferrara N (1989) Vascular endothelial growth factor is a secreted angiogenic mitogen. Science, 246, 13061309.
  • Margolis BL, Lax I, Kris R, Dombalagian M, Honegger AM, Howk R, Givol D, Ullrich A and Schlessinger J (1989) All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. J Biol Chem, 264, 1066710671.
  • Matthews W, Jordan CT, Gavin M, Jenkins NA, Copeland NG and Lemischka IR (1991) A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc Natl Acad Sci USA, 88, 90269030.
  • Middlemas DS, Meisenhelder J and Hunter T (1994) Identification of TrkB autophosphorylation sites and evidence that phospholipase C-γ1 is a substrate of the TrkB receptor. J Biol Chem, 269, 54585466.
  • Millauer B, Wizigmann-Voos S, Schnurch H, Martinez R, Moller NP, Risau W and Ullrich A (1993) High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell, 72, 835846.
  • Mohammadi M et al. (1991) A tyrosine-phosphorylated carboxyl-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-γ1. Mol Cell Biol, 11, 50685078.
  • Mustonen T and Alitalo K (1995) Endothelial receptor tyrosine kinases involved in angiogenesis. J Cell Biol, 129, 895898.
  • Namba K, Abe M, Saito S, Satake M, Ohmoto T, Watanabe T and Sato Y (2000) Indispensable role of the transcription factor PEBP2/CBF in angiogenic activity of a murine endothelial cell MSS31. Oncogene, 19, 106114.
  • Nishizuka Y (1992) Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science, 258, 607614.
  • Obermeier A, Halfter H, Wiesmuller K-H, Jung G, Schlessinger J and Ullrich A (1993) Tyrosine 785 is a major determinant of Trk–substrate interaction. EMBO J, 12, 933941.
  • Pepper MS, Ferrara N, Orci L and Montesano R (1991) Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun, 181, 902906.
  • Ronnstrand L, Mori S, Arridsson A-K, Ericksson A, Christer W, Hellman U, Claesson-Welsh L and Heldin C-H (1992) Identification of two C-terminal autophosphorylation sites in the PDGF β-receptor: involvement in the interaction with phospholipase C-γ. EMBO J, 11, 39113919.
  • Rotin D et al. (1992) SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase Cγ. EMBO J, 11, 559567.
  • Sarzani R, Arnaldi G, De Pirro R, Moretti P, Schiaffino S and Rappelli A (1992) A novel endothelial tyrosine kinase cDNA homologous to platelet-derived growth factor receptor cDNA. Biochem Biophys Res Commun, 186, 706714.
  • Sawano A, Takahashi T, Yamaguchi S and Shibuya M (1997) The phosphorylated 1169-tyrosine containing region of Flt-1 kinase (VEGFR-1) is a major binding site for PLCγ. Biochem Biophys Res Commun, 238, 487491.
  • Seetharam L, Gotoh N, Maru Y, Neufeld G, Yamaguchi S and Shibuya M (1995) A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF. Oncogene, 10, 135147.
  • Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS and Dvorak HF (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science, 219, 983985.
  • Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein M, Wu X-F, Breitman ML and Schuh AC (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature, 376, 6266.
  • Shibuya M (1995) Role of VEGF-flt receptor system in normal and tumor angiogenesis. Adv Cancer Res, 67, 281316.
  • Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matushime H and Sato M (1990) Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene, 5, 519524.
  • Songyang Z et al. (1993) SH2 domains recognize specific phospho peptide sequences. Cell, 72, 767778.
  • Takahashi T and Shibuya M (1997) The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-γ pathway and partially induces mitotic signals in NIH3T3 fibroblasts. Oncogene, 14, 20792089.
  • Takahashi T, Ueno H, and Shibuya M (1999) VEGF activates protein kinase C-dependent, but Ras-independent Raf–MEK–MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene, 18, 22212230.
  • Terman BI, Carrion ME, Kovacs E, Rasmussen BA, Eddy RL and Shows TB (1991) Identification of a new endothelial cell growth factor receptor tyrosine kinase. Oncogene, 6, 16771683.
  • Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D and Böhlen P (1992) Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun, 187, 15791586.
  • Unemori EN, Ferrara N, Bauer EA and Amento EP (1992) Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J Cell Physiol, 153, 557562.
  • Valius M, Bazenet C and Kazlauskas A (1993) Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor β subunit and are required for binding of phospholipase C-γ and a 64-kilodalton protein, respectively. Mol Cell Biol, 13, 133143.
  • Waltenberger J, Claesson-Welsh L, Siegbahn A, Shibuya M, and Heldin C-H (1994) Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor. J Biol Chem, 269, 2698826995.
  • Yamane A, Seetharam L, Yamaguchi S, Gotoh N, Takahashi T, Neufeld G and Shibuya M (1994) A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1). Oncogene, 9, 26832690.
  • Yanai N, Satoh T and Obinata M (1991) Endothelial cells create a hematopoietic inductive microenvironment preferential to erythro poiesis in the mouse spleen. Cell Struct Funct, 16, 8793.