Genetics of Alcoholism Using Intermediate Phenotypes


  • Supported by the Office of Research on Minority Health (M-AE, DG); NIAAA Grant AA05526, the Veterans Affairs Research Service, and funds provided by the State of California for medical research on alcoholism and substance abuse through the University of California, San Francisco (MAS); and NIAAA Grants AA10522-05 and AA10522-0551 (BAJ).

Mary-Anne Enoch, MD, NIH/NIAAA/DICBR/LNG, 12420 Parklawn Dr., Park 5 Bldg., Room 451, MSC 8110, Bethesda, MD 20892-8110; Fax: 301-443-8579; E-mail:


This article represents the proceedings of a symposium at the 2002 meeting of the Research Society on Alcoholism in San Francisco, CA. It was organized by Mary-Anne Enoch and David Goldman and chaired by David Goldman. The presentations were (1) Two functional polymorphisms and their intermediate phenotypes in complex behaviors: COMT/executive cognition and anxiety and HTT/anxiety, by David Goldman; (2) Role of the EEG in determining genetic risk for alcoholism and anxiety disorders, by Mary-Anne Enoch; (3) The response to alcohol as an intermediate phenotype for alcoholism, by Marc A. Schuckit; and (4) Pharmacogenomic approaches to alcoholism treatment: toward a hypothesis, by Bankole A. Johnson.