Olfactory Function and Olfactory Bulb Volume in Patients with Postinfectious Olfactory Loss
Article first published online: 2 JAN 2009
Copyright © 2006 The Triological Society
Volume 116, Issue 3, pages 436–439, March 2006
How to Cite
Rombaux, P., Mouraux, A., Bertrand, B., Nicolas, G., Duprez, T. and Hummel, T. (2006), Olfactory Function and Olfactory Bulb Volume in Patients with Postinfectious Olfactory Loss. The Laryngoscope, 116: 436–439. doi: 10.1097/01.MLG.0000195291.36641.1E
- Issue published online: 2 JAN 2009
- Article first published online: 2 JAN 2009
- Manuscript Accepted: 25 OCT 2005
Objective: The study aimed to investigate whether the degree of postinfectious olfactory loss is reflected in volume of the olfactory bulb (OB).
Study Design: Retrospective study of 26 patients with postinfectious olfactory loss.
Materials and Methods: Olfactory function was assessed with the “Sniffin Sticks” test kit, and the magnetic resonance imaging study focused on OB volume and the olfactory sulcus.
Results: The study revealed that 1) OB volume varies with regard to olfactory function, 2) OB volume decreases with duration of olfactory loss, and 3) patients with parosmia had smaller OB volumes than patients who did not report such smell distortions, although their overall olfactory function was not significantly different from each other.
Conclusion: The study emphasizes that OB volume is a gauge of olfactory function.