Middle Section Meeting of the Triological Society, January 2005.
Parathyroid Adenoma Localization: Surgeon-Performed Ultrasound Versus Sestamibi†
Article first published online: 2 JAN 2009
Copyright © 2006 The Triological Society
Volume 116, Issue 8, pages 1380–1384, August 2006
How to Cite
Steward, D. L., Danielson, G. P., Afman, C. E. and Welge, J. A. (2006), Parathyroid Adenoma Localization: Surgeon-Performed Ultrasound Versus Sestamibi. The Laryngoscope, 116: 1380–1384. doi: 10.1097/01.mlg.0000227957.06529.22
- Issue published online: 2 JAN 2009
- Article first published online: 2 JAN 2009
- Manuscript Accepted: 13 MAR 2006
- primary hyperparathyroidism;
- minimally invasive parathyroidectomy
Objectives: Compare surgeon-performed ultrasound versus sestamibi for preoperative parathyroid adenoma localization.
Study Design: Single-institutional cohort.
Methods: One hundred six consecutive patients undergoing parathyroidectomy at an academic institution between 2004 to 2005 were included. Of those, 103 underwent both surgeon-performed ultrasound and sestamibi-Tc99m localization preoperatively. Primary outcome is sensitivity for adenoma localization to correct quadrant (right vs. left, superior vs. inferior).
Results: Hypercalcemia resolved in 97% of patients. Sensitivities for correct quadrant localization for ultrasound versus sestamibi were 87% versus 58% (P < .001). Specificities were 95%. Positive and negative predictive values were 85% versus 78% and 96% versus 87%, respectively. Combined sensitivity was 93%. Sensitivities for correct side localization were 91% and 74% (P = .002).
Conclusions: Ultrasound appears more sensitive than sestamibi for localization to correct quadrant or side when performed in-office by the author in this cohort.