Eastern Section of the Triological Society Meeting, Toronto, Canada, January 20–22, 2006.
Office Steroid Injections of the Larynx†
Article first published online: 2 JAN 2009
Copyright © 2006 The Triological Society
Volume 116, Issue 10, pages 1735–1739, October 2006
How to Cite
Mortensen, M. and Woo, P. (2006), Office Steroid Injections of the Larynx. The Laryngoscope, 116: 1735–1739. doi: 10.1097/01.mlg.0000231455.19183.8c
- Issue published online: 2 JAN 2009
- Article first published online: 2 JAN 2009
- Manuscript Accepted: 22 MAY 2006
- Vocal nodules;
- office steroid injection;
- vocal fold scar;
Objective: Steroid injection into the larynx has been sporadically reported as helpful in benign lesions of the larynx. Its role in laryngology remains unclear. This study reviews the indications and results of 47 steroid injections in 34 patients in an office setting.
Methods: The authors conducted a retrospective review of 47 injections in 34 patients. Methylprednisolone acetate suspension, USP (40 mg/mL), was injected by indirect laryngoscopy under local anesthesia. Results were evaluated by stroboscopy and by perceptual evaluation of the GRABS scale before and after injection. Pre- versus postinjection ratings were compared by paired t test.
Results: Indications for injection were: 1) postoperative scar with local stiffness (12 patients), 2) vocal nodules and polyp (18 patients), and 3) sarcoidosis/granuloma (4 patients). Steroid injections were done in professional singers instead of repeated oral administration of steroids and/or to avoid surgery in patients with polyps and cysts. Improvement was noted in 28 of 34 (82%). Eleven of the 18 patients with polyps and nodules had significant improvement and avoided surgery. Vocal fold scars improved after injection with an improved voice grade (P < .01), an improved amplitude (P < .05), and improved mucosal wave (P < .05). There were no complications. Only two patients could not tolerate office injection.
Conclusion: Office steroid injections are a valuable adjunct in management of vocal fold scars, polyps, nodules, and granulomas.