This research was supported by a grant from the Department of Veterans Affairs, Philadelphia VA Medical Center, Competitive Pilot Project Fund.
Gustatory Impairment in Patients Undergoing Head and Neck Irradiation†
Article first published online: 2 JAN 2009
Copyright © 2008 The Triological Society
Volume 118, Issue 1, pages 24–31, January 2008
How to Cite
Mirza, N., Machtay, M., Devine, P. A., Troxel, A., Abboud, S. K. and Doty, R. L. (2008), Gustatory Impairment in Patients Undergoing Head and Neck Irradiation. The Laryngoscope, 118: 24–31. doi: 10.1097/MLG.0b013e318155a276
- Issue published online: 2 JAN 2009
- Article first published online: 2 JAN 2009
- Manuscript Accepted: 19 JUL 2007
- taste pores
Objectives: To determine whether radiation alters taste function and structure.
Research Design: Prospective, longitudinal study.
Methodology: Testing prior to starting radiation, and 2 weeks, 2 months, and 6 months after completing radiation.
Results: Relative to controls, patients had lower taste identification test scores for bitter, salty, and sour tastes. Sour taste also showed a significant group-by-time interaction (P = .03). Taste pores were decreased in the irradiated group, with a significant group-by-time interaction (P = .03).
Conclusion: Head and neck cancer patients have decreased taste function, and radiation adversely affected sour taste and taste pores.