Persistent Allergic Rhinitis Includes Different Pathophysiologic Types
Article first published online: 2 JAN 2009
Copyright © 2008 The Triological Society
Volume 118, Issue 3, pages 385–388, March 2008
How to Cite
Ciprandi, G., Cirillo, I. and Pistorio, A. (2008), Persistent Allergic Rhinitis Includes Different Pathophysiologic Types. The Laryngoscope, 118: 385–388. doi: 10.1097/MLG.0b013e31815dd50b
- Issue published online: 2 JAN 2009
- Article first published online: 2 JAN 2009
- Manuscript Accepted: 11 OCT 2007
- Allergic rhinitis;
- perennial allergens
Background: Allergy rhinitis is typically classified as seasonal allergy rhinitis (SAR) and perennial allergy rhinitis (PAR). More recently, the Allergic Rhinitis and its Impact on Asthma document proposed the intermittent (ITR) and persistent forms (PER). However, it has been previously reported that each single allergen may induce different clinical and pathophysiologic features.
Objective: The aim of the study was to test the hypothesis that the type of causal allergen might characterize pathophysiologic differences in a cohort of patients with PER.
Methods: Three hundred nineteen patients, sailors of the Italian Navy, with moderate-severe PER were prospectively and consecutively evaluated with clinical evaluation, skin prick test, rhinomanometry, and nasal decongestion test.
Results: Patients with pollen allergy showed significantly more severe symptoms, lower nasal airflow, and higher response to decongestion test than patients with allergy to perennial allergens (P < .0001).
Conclusion: This study provides evidence that patients with PER may show different pathophysiologic patterns depending on the type of causal allergen.