Chapter 4.2 Crystallization of membrane proteins
Crystallography of biological macromolecules
Second Online Edition (2012)
Part 4. Crystallization
Published Online: 14 APR 2012
© International Union of Crystallography 2006
International Tables for Crystallography
How to Cite
Michel, H. 2012. Crystallization of membrane proteins. International Tables for Crystallography. F:4:4.2:122–128.
- Published Online: 14 APR 2012
The crystallization of membrane proteins is described. The topics covered include the principles of membrane-protein crystallization, general properties of detergents relevant to membrane-protein crystallization, the ‘small amphiphile concept’, membrane-protein crystallization with the help of antibody Fv fragments and membrane-protein crystallization using cubic bicontinuous lipidic phases. General recommendations on crystallizing membrane proteins are provided, and membrane proteins with known structures and potentially useful detergents are tabulated.
- antibody Fv fragments in crystallization of membrane proteins;
- cubic bicontinuous lipidic phases;
- membrane proteins;
- small amphiphile concept