Chapter 8.2 Laue crystallography: time-resolved studies

Crystallography of biological macromolecules

Second Online Edition (2012)

Part 8. Synchrotron crystallography

  1. K. Moffat

Published Online: 14 APR 2012

DOI: 10.1107/97809553602060000823

International Tables for Crystallography

International Tables for Crystallography

How to Cite

Moffat, K. 2012. Laue crystallography: time-resolved studies. International Tables for Crystallography. F:8:8.2:205–210.

Author Information

  1. Department of Biochemistry and Molecular Biology, The Center for Advanced Radiation Sources, and The Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, USA

Publication History

  1. Published Online: 14 APR 2012


The term ‘Laue diffraction’ describes the process of X-ray scattering that occurs when a stationary crystal is illuminated by a polychromatic beam of X-rays. Recent developments in Laue diffraction have depended on three main advances: the use of very intense polychromatic synchrotron sources; the realization that the so-called energy-overlap or overlapping-orders problem in Laue diffraction is theoretically tractable, of limited extent and could be overcome experimentally; and the development of appropriate algorithms and suitable software to address the energy-overlap, spatial-overlap and wavelength-normalization problems. This chapter covers the principles of Laue diffraction, practical considerations in the Laue technique and time-resolved experiments.


  • Laue diffraction;
  • data redundancy;
  • radiation damage;
  • synchrotron radiation;
  • time-resolved studies;
  • wavelength normalization curve