Chapter 14.2 Multiwavelength anomalous diffraction

Crystallography of biological macromolecules

Second Online Edition (2012)

Part 14. Anomalous dispersion

  1. J. L. Smith1,
  2. W. A. Hendrickson2

Published Online: 14 APR 2012

DOI: 10.1107/97809553602060000845

International Tables for Crystallography

International Tables for Crystallography

How to Cite

Smith, J. L. and Hendrickson, W. A. 2012. Multiwavelength anomalous diffraction. International Tables for Crystallography. F:14:14.2:373–378.

Author Information

  1. 1

    Department of Biological Sciences, Purdue University, West Lafayette, IN 47907–1392, USA

  2. 2

    Department of Biochemistry, College of Physicians & Surgeons of Columbia University, 630 West 168th Street, New York, NY 10032, USA

Publication History

  1. Published Online: 14 APR 2012


Multiwavelength anomalous diffraction (MAD) is described, including experimental considerations, estimating the phasing signal, data handling and labels for biological macromolecules.


  • anomalous-scatterer labels for MAD;
  • anomalous scattering;
  • anomalous scattering factors;
  • MAD;
  • multiwavelength anomalous diffraction;
  • phasing;
  • scattering factors;
  • structure solution