Chapter 18.12 Structure determination in the presence of twinning by merohedry
Crystallography of biological macromolecules
Second Online Edition (2012)
Part 18. Refinement
Published Online: 14 APR 2012
© International Union of Crystallography 2006
International Tables for Crystallography
How to Cite
Yeates, T. O. and Sawaya, M. R. 2012. Structure determination in the presence of twinning by merohedry. International Tables for Crystallography. F:18:18.12:548–551.
- Published Online: 14 APR 2012
This chapter details strategies for determining structures based on intensity data suffering from twinning. Progress can often be made in the early stages of structure determination without taking the twinning into account, whereas proper refinement of structures must account for the effects of twinning. Complications that can occur when handling anomalous-scattering information are discussed. Opportunities are identified for more formal treatments of the problem of phasing twinned data. The facility with which twinning can be analysed and discriminated from local noncrystallographic symmetry during the final stages of analysis is emphasized.
- merohedral twinning;
- structure determination