SEARCH

SEARCH BY CITATION

Keywords:

  • lectin;
  • Pseudomonas aeruginosa;
  • cystic fibrosis.

Carbohydrate recognition plays a role in the pathogenesis of Pseudomonas aeruginosa, a common cause of opportunistic infection in humans. Crystals of a carbohydrate-binding protein from P. aeruginosa, lectin PA-1, have now been obtained. The crystals belong to space group I222, with unit-cell parameters a = 40.25, b = 72.30, c = 133.82 Å, and diffract to beyond 1.9 Å resolution on a rotating-anode X-ray source. Details of crystal-growth conditions, diffraction data collection and processing are reported.