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In the asymmetric unit of the title compound, [Cd(C20H22N2O4)(H2O)2]·2.5H2O, there are five water molecules and two independent mononuclear complex molecules in which the CdII ions are in distorted octahedral coordination environments, defined by N2O4 donor sets. In the crystal structure, extensive hydrogen bonding links molecules into one-dimensional chains along the b axis.