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A class of statistical models is proposed for longitudinal network data. The dependent variable is the changing (or evolving) relation network, represented by two or more observations of a directed graph with a fixed set of actors. The network evolution is modeled as the consequence of the actors making new choices, or withdrawing existing choices, on the basis of functions, with fixed and random components, that the actors try to maximize. Individual and dyadic exogenous variables can be used as covariates. The change in the network is modeled as the stochastic result of network effects (reciprocity, transitivity, etc.) and these covariates. The existing network structure is a dynamic constraint for the evolution of the structure itself. The models are continuous-time Markov chain models that can be implemented as simulation models. The model parameters are estimated from observed data. For estimating and testing these models, statistical procedures are proposed that are based on the method of moments. The statistical procedures are implemented using a stochastic approximation algorithm based on computer simulations of the network evolution process.