SEARCH

SEARCH BY CITATION

Keywords:

  • 16S rRNA gene;
  • Buruli ulcer;
  • cutaneous infection;
  • non-tuberculous mycobacterial infection;
  • polymerase chain reaction;
  • species identification

Abstract

There is evidence that the incidence of cutaneous non-tuberculous mycobacterial (NTM) infection is increasing worldwide. Novel culture methods and new analytical procedures have led to significant advancements in understanding the origin and progression of NTM infections. Differential identification of NTM isolates is important because culture characteristics and/or sensitivity to anti-mycobacterium drugs vary between different mycobacterial species. In this manuscript, we describe the latest diagnostic techniques for cutaneous NTM infection and show how these methodologies can be used for the diagnosis of Buruli ulcer in Japan.