Genetics of hypopigmentary disorders

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It is my great honor to welcome you to this special issue of the Journal of Dermatology as a guest editor, that highlights “genetics of hypopigmentary disorders”. Some hypopigmentary disorders may be easy to diagnose because of their own characteristic symptoms. However, the pathomechanisms remain unknown in the majority of hypopigmentary diseases. Also, effective and safe treatments have not been established in many of these diseases. In the past 10 years, there has been remarkable progress made in understanding the mechanisms of the pigmentation and pathogenesis of some diseases by investigating the genetics of hypopigmentary disorders.

In this issue, recent developments in hypopigmentary disorders are reviewed focusing on the following five diseases: (i) vitiligo (by Spritz); (ii) oculocutaneous albinism in Europe (by Mártìnez-Garcìa and Montoliu); (iii) Hermansky–Pudlak syndrome (by Wei et al.); (iv) piebaldism (by Oiso et al.); and (v) dyschromatosis symmetrica hereditaria (by Hayashi and Suzuki). Each article contributor in this issue is an expert in his field. I gratefully appreciate their contribution of these excellent review articles. I hope that a lot of readers will enjoy this special issue.

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