Cephalosporin resistant Escherichia coli from cancer patients in Cairo, Egypt



Caterina Mammina, Department of Sciences for Health Promotion and Mother-Child Care “G. D'Alessandro”, Via del Vespro 133, Palermo I-90127, Italy.

Tel: +39 0916553623; fax: +39 0916553641; email: caterina.mammina@unipa.it


Cephalosporin-resistant Escherichia coli has been increasingly reported worldwide. In this study, 32 cephalosporin resistant E. coli isolates identified from cancer patients in Cairo, Egypt in 2009–2010 were analyzed. Twenty-three were of phylogenetic group D, seven A and one each B1 and B2. By rep-PCR 15 phylogroup D isolates were grouped in four clusters, one with sequence type (ST) 405 and three ST68. Seventeen isolates showed single patterns. blaCTX-M-15 and aac(6')-Ib-cr were the most common resistance determinants. blaOXA-48 and blaVIM were also detected. Multidrug resistant E. coli seriously affects healthcare, especially in immunocompromised hosts, such as cancer patients.