• 1
    Ruggiero P. (2010) Helicobacter pylori and inflammation. Curr Pharm Des 16: 422435.
  • 2
    Choi I.J., Fujimoto S., Yamauchi K., Graham D.Y., Yamaoka Y. (2007) Helicobacter pylori environmental interactions: effect of acidic conditions on H. pylori-induced gastric mucosal interleukin-8 production. Cell Microbiol 9: 245769.
  • 3
    Farshad S., Rasouli M., Jamshidzadeh A., Hosseinkhani A., Japoni A., Alborzi A., Taghavi A., Kazemi Asl H., Ranjbar R. (2010) IL-1ß (+3953 C/T) and IL-8 (-251 A/T) gene polymorphisms in H. pylori mediated gastric disorders. Iran J Immunol 7: 96108.
  • 4
    Ben-Baruch A., Michiel D.F., Oppenheim J.J. (1995) Signals and receptors involved in recruitment of inflammatory cells. J Biol Chem 70: 117036.
  • 5
    Miller M.D., Krangel M.S. (1992) Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Crit Rev Immunol 12: 1746.
  • 6
    Yoshimura T., Matsushima K., Oppenheim J.J., Leonard E.J. (1987) Neutrophil chemotactic factor produced by lipopolysaccharide (LPS)-stimulated human blood mononuclear leukocytes: partial characterization and separation from interleukin-1 (IL-1). J Immunol 139: 78893.
  • 7
    Cacalano G., Lee J., Kikly K., Ryan A.M., Pitts-Meek S., Hultgren B., Wood W.I., Moore M.W. (1994) Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog. Science 265: 6824.
  • 8
    Koch A.E., Polverini P.J., Kunkel S.L., Harlow L.A., Di Pietro L.A., Elner V.M., Elner S.G., Strieter R.M. (1992) Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 258: 1798801.
  • 9
    Strieter R.M., Koch A.E., Antony V.B., Fick R.B., Jr, Standiford T.J., Kunkel S.L. (1994) The immunopathology of chemotactic cytokines: the role of interleukin-8 and monocyte chemoattractant protein-1. J Lab Clin Med 123: 18397.
  • 10
    Kamali-Sarvestani E., Bazargani A., Masoudian M., Lankarani K., Taghavi A.R., Saberifiroozi M. (2006) Association of H. pylori cagA and vacA genotypes and IL-8 gene polymorphisms with clinical outcome of infection in Iranian patients with gastrointestinal diseases. World J Gastroenterol 12: 520510.
  • 11
    Ren K., Torres R. (2009) Role of interleukin-1beta during pain and inflammation. Brain Res Rev 60: 5764.
  • 12
    Zhong W., Yin H., Xie L. (2009) Expression and potential role of major inflammatory cytokines in experimental keratomycosis. Mol Vis 15: 130311.
  • 13
    Andreou K., Rajendran R., Krstic-Demonacos M., Demonacos C. (2012) Regulation of CXCR4 gene expression in breast cancer cells under diverse stress conditions. Int J Oncol 41: 22539.
  • 14
    Rahimi H.R., Shiri M., Razmi A. (2012) Antidepressants can treat inflammatory bowel disease through regulation of the nuclear factor-κB/nitric oxide pathway and inhibition of cytokine production: a hypothesis. World J Gastrointest Pharmacol Ther 3: 835.
  • 15
    Farshad S., Alborzi A., Abbasian A. (2007) Association of H. pylori virulence genes CagA, VacA and UreAB with ulcer and nonulcer diseases in Iranian population. Pak J Biol Sci 10: 11859.
  • 16
    Farshad S., Japoni A., Alborzi A., Hosseini M. (2007) Restriction fragment length polymorphism of virulence genes cagA, vacA and ureAB of Helicobacter pylori strains isolated from Iranian patients with gastric ulcer and nonulcer disease. Saudi Med J 28: 52934.
  • 17
    Rudnicka K., Włodarczyk M., Moran A.P., Rechciński T., Miszczyk E., Matusiak A., Szczęsna E., Walencka M., Rudnicka W., Chmiela M. (2012) Helicobacter pylori antigens as potential modulators of lymphocytes' cytotoxic activity. Microbiol Immunol 56: 6275.
  • 18
    Ziver T., Yuksel P., Ipek G., Yekeler I., Bayramoglu Z., Tireli E., Saribas S., Aslan M., Yalvac S.D., Ozdomanic I., Torlak Z., Dirican A., Torun M.M., Kocazeybek B. (2010) Aneurysm and Helicobacter pylori relationship: the seropositivity of CagA, VacA and other antigens of Helicobacter pylori in abdominal and ascending aortic aneurysms. New Microbiol 33: 23342.
  • 19
    Handa O., Naito Y., Yoshikawa T. (2007) CagA protein of Helicobacter pylori: a hijacker of gastric epithelial cell signaling. Biochem Pharmacol 73: 1697702.
  • 20
    Maciorkowska E., Kaczmarski M., Kemona A. (1999) Concentration of selected cytokines of gastric mucosa in children with Helicobacter pylori infection. Med Sci Monit 5: 11405.
  • 21
    Lopes A.I., Marianne Q.J., Palha A., Ruivo J., Monteiro L., Oleastro M., Santos A., Fernandes A. (2005) Cytokine expression in pediatric Helicobacter pylori infection. Clin Diagn Lab Immunol 12: 9941002.
  • 22
    Ritter B., Kilian P., Reboll M.R., Resch K., Distefano J.K., Frank R., Beil W., Nourbakhsh M. (2011) Differential effects of multiplicity of infection on Helicobacter pylori-induced signaling pathways and interleukin-8 gene transcription. J Clin Immunol 31: 608.
  • 23
    Chai L.A., Netea M.G., Teerenstra S., Earnest A., Vonk A.G., Schlamm H.T., Herbrecht R., Troke P.F., Kullberg B.J. (2010) Early proinflammatory cytokines and C-reactive protein trends as predictors of outcome in invasive Aspergillosis. J Infect Dis 202: 145462.
  • 24
    Sun K.H., Yu C.L., Tang S.J., Sun G.H. (2000) Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha from normal human mononuclear cells involving in the lupus pathogenesis. Immunology 99: 35260.
  • 25
    Al-Attiyah R., El-Shazly A., Mustafa A.S. (2012) Comparative analysis of spontaneous and mycobacterial antigen-induced secretion of Th1, Th2 and pro-inflammatory cytokines by peripheral blood mononuclear cells of tuberculosis patients. Scand J Immunol 75: 62332.
  • 26
    Del Giudice G., Covacci A., Telford J.L., Montecucco C., Rappuoli R. (2001) The design of vaccines against Helicobacter pylori and their development. Annu Rev Immunol 19: 52363.
  • 27
    Kayhan B., Arasli M., Eren H., Aydemir S., Kayhan B., Aktas E., Tekin I. (2008) Analysis of peripheral blood lymphocyte phenotypes and Th1/Th2 cytokines profile in the systemic immune responses of Helicobacter pylori infected individuals. Microbiol Immunol 52: 5318.
  • 28
    Fan X., Chau A., Shahi C., Mcdevitt J., Keeling P., Kelleher D. (1994) Gastric T lymphocyte responses to Helicobacter pylori in patients with H. pylori colonization. Gut 35: 137984.
  • 29
    Sewald X., Jiménez-Soto L., Haas R. (2011) PKC-dependent endocytosis of the Helicobacter pylori vacuolating cytotoxin in primary T lymphocytes. Cell Microbiol 13: 48296.
  • 30
    Paziak-Domańska B., Chmiela M., Jarosińska A., Rudnicka W. (2000) Potential role of CagA in the inhibition of T cell reactivity in Helicobacter pylori infections. Cell Immunol 202: 1369.
  • 31
    Sundrud M.S., Torres V.J., Unutmaz D., Cover T.L. (2004) Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proc Natl Acad Sci USA 101: 772732.
  • 32
    Torres V.J., Van Compernolle S.E., Sundrud M.S., Unutmaz D., Cover T.L. (2007) Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets. J Immunol 179: 543340.
  • 33
    Gebert B., Fischer W., Weiss E., Hoffmann R., Haas R. (2003) Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation. Science. 301: 1099102.
  • 34
    Zabaleta J., McGee D.J., Zea A.H., Hernández C.P., Rodriguez P.C., Sierra R.A., Correa P., Ochoa A.C. (2004) Helicobacter pylori arginase inhibits T cell proliferation and reduces the expression of the TCR zeta-chain (CD3zeta). J Immunol 173: 58693.
  • 35
    Grebowska A., Moran A.P., Bielanski W., Matusiak A., Rechcinski T., Rudnicka K., Baranowska A., Rudnicka W., Chmiela M. (2010) Helicobacter pylori lipopolysaccharide activity in human peripheral blood mononuclear leukocyte cultures. J Physiol Pharmacol 61: 43742.
  • 36
    Chen W., Shu D., Chandwick V.S. (2000) Inhibition of mitogen-induced murine lymphocyte proliferation by Helicobacter pylori cell-free extract. J Gasteroenterol Hepatol 15: 10006.
  • 37
    Gerhard M., Schmees C., Voland P., Endres N., Sander M., Reindl W., Rad R., Oelsner M., Decker T., Mempel M., Hengst L., Prinz C. (2005) A secreted low-molecular-weight protein from Helicobacter pylori induces cell-cycle arrest of T cells. Gastroenterology 128: 132739.