• 1
    Dai T., Huang Y.Y., Hamblin M.R. (2009) Photodynamic therapy for localized infections—state of the art. Photodiagnosis Photodyn Ther 6: 17088.
  • 2
    Goto B., Iriuchishima T., Horaguchi T., Tokuhashi Y., Nagai Y., Harada T., Saito, A., Aizawa, S. (2011) Therapeutic effect of photodynamic therapy using Na-pheophorbide a on osteomyelitis models in rats. Photomed Laser Surg 29: 1839.
  • 3
    Iriuchishima T., Saito A., Aizawa S., Taira K., Yamamoto T., Ryu J. (2008) The minimum influences for murine normal joint tissue by novel bactericidal treatment and photodynamic therapy using Na-pheophorbide a for septic arthritis. Photomed Laser Surg 26: 1538.
  • 4
    Jori G., Fabris C., Soncin M., Ferro S., Coppellotti O., Dei D., Fantetti L., Chiti, G., Roncucci, G. (2006) Photodynamic therapy in the treatment of microbial infections: basic principles and perspective applications. Lasers Surg Med 38: 46881.
  • 5
    Ziegelhoffer E.C., Donohue T.J. (2009) Bacterial responses to photo-oxidative stress. Nat Rev Microbiol 7: 85663.
  • 6
    Imlay J.A. (2003) Pathways of oxidative damage. Annu Rev Microbiol 57: 395418.
  • 7
    Park J.H., Moon Y.H., Bang I.S., Kim Y.C., Kim S.A., Ahn S.G., Yoon J.H. (2010) Antimicrobial effect of photodynamic therapy using a highly pure chlorin e6. Lasers Med Sci 25: 70510.
  • 8
    Chan P.F., Foster S.J. (1998) The role of environmental factors in the regulation of virulence-determinant expression in Staphylococcus aureus 8325-4. Microbiology 144(Pt 9): 246979.
  • 9
    Ahn M.Y., Kwon S.M., Kim Y.C., Ahn S.G., Yoon J.H. (2012) Pheophorbide a-mediated photodynamic therapy induces apoptotic cell death in murine oral squamous cell carcinoma in vitro and in vivo. Oncol Rep 27: 17728.
  • 10
    Yamamoto T., Iriuchishima T., Aizawa S., Okano T., Goto B., Nagai Y., Horaguchi T., Ryu J., Saito A. (2009) Bactericidal effect of photodynamic therapy using Na-pheophorbide a: evaluation of adequate light source. Photomed Laser Surg 27: 84953.
  • 11
    Cassat J., Dunman P.M., Murphy E., Projan S.J., Beenken K.E., Palm K.J., Yang S-J., Rice K.C., Bayles K.W., Smeltzer M.S. (2006) Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390. Microbiology 152: 307590.
  • 12
    Dunman P.M., Murphy E., Haney S., Palacios D., Tucker-Kellogg G., Wu S., Brown E.L., Zagursky R.J., Shlaes D., Projan S.J. (2001) Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci. J Bacteriol 183: 734153.
  • 13
    Clements M.O., Foster S.J. (1999) Stress resistance in Staphylococcus aureus. Trends Microbiol 7: 45862.
  • 14
    Coombs G.W., Monecke S., Pearson J.C., Tan H.L., Chew Y.K., Wilson L., Ehricht R., O'Brien F.G., Christiansen K.J. (2011) Evolution and diversity of community-associated methicillin-resistant Staphylococcus aureus in a geographical region. BMC Microbiol 11: 215.
  • 15
    Novick R.P. (2003) Autoinduction and signal transduction in the regulation of staphylococcal virulence. Mol Microbiol 48: 142949.
  • 16
    Wright J.S., III, Jin R., Novick R.P. (2005) Transient interference with staphylococcal quorum sensing blocks abscess formation. Proc Natl Acad Sci USA 102: 16916.
  • 17
    Abdelnour A., Arvidson S., Bremell T., Ryden C., Tarkowski A. (1993) The accessory gene regulator (agr) controls Staphylococcus aureus virulence in a murine arthritis model. Infect Immun 61: 387985.
  • 18
    Booth M.C., Atkuri R.V., Nanda S.K., Iandolo J.J., Gilmore M.S. (1995) Accessory gene regulator controls Staphylococcus aureus virulence in endophthalmitis. Invest Ophthalmol Vis Sci 36: 182836.
  • 19
    Gillaspy A.F., Hickmon S.G., Skinner R.A., Thomas J.R., Nelson C.L., Smeltzer M.S. (1995) Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis. Infect Immun 63: 337380.
  • 20
    Boles B.R., Horswill A.R. (2008) Agr-mediated dispersal of Staphylococcus aureus biofilms. PLoS Pathog 4: e1000052.
  • 21
    Lauderdale K.J., Boles B.R., Cheung A.L., Horswill A.R. (2009) Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation. Infect Immun 77: 162335.
  • 22
    Furukawa S., Kuchma S.L., O'Toole G.A. (2006) Keeping their options open: acute versus persistent infections. J Bacteriol 188: 12117.
  • 23
    Fowler V.G., Jr., Sakoulas G., McIntyre L.M., Meka V.G., Arbeit R.D., Cabell C.H., Stryjewski M.E., Eliopoulos G.M., Reller L.B., Corey G.R., Jones T., Lucindo N., Yeaman M.R., Bayer, A.S. (2004) Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. J Infect Dis 190: 11409.
  • 24
    Blevins J.S., Beenken K.E., Elasri M.O., Hurlburt B.K., Smeltzer M.S. (2002) Strain-dependent differences in the regulatory roles of sarA and agr in Staphylococcus aureus. Infect Immun 70: 47080.
  • 25
    Yarwood J.M., Paquette K.M., Tikh I.B., Volper E.M., Greenberg E.P. (2007) Generation of virulence factor variants in Staphylococcus aureus biofilms. J Bacteriol 189: 79617.
  • 26
    Kawamura H., Nishi J., Imuta N., Tokuda K., Miyanohara H., Hashiguchi T., Zenmyo M., Yamamoto T., Ijiri K., Kawano Y., Komita S. (2011) Quantitative analysis of biofilm formation of methicillin-resistant Staphylococcus aureus (MRSA) strains from patients with orthopaedic device-related infections. FEMS Immunol Med Microbiol 63: 105.
  • 27
    Sakoulas G., Moellering R.C., Jr., Eliopoulos G.M. (2006) Adaptation of methicillin-resistant Staphylococcus aureus in the face of vancomycin therapy. Clin Infect Dis 42 (Suppl 1): S4050.
  • 28
    Sakoulas G., Eliopoulos G.M., Moellering R.C., Jr., Wennersten C., Venkataraman L., Novick R.P., Gold H.S. (2002) Accessory gene regulator (agr) locus in geographically diverse Staphylococcus aureus isolates with reduced susceptibility to vancomycin. Antimicrob Agents Chemother 46: 1492502.
  • 29
    Schwan W.R., Langhorne M.H., Ritchie H.D., Stover, C.K. (2003) Loss of hemolysin expression in Staphylococcus aureus agr mutants correlates with selective survival during mixed infections in murine abscesses and wounds. FEMS Immunol Med Microbiol 38: 238.