An approach for personality-based self-discrepancy (PBSD) measurement is proposed, whereby self-beliefs and incongruities among their contents are assessed with respect to five-factor model (FFM) semantic dimensions. Selves Questionnaire attributes from 191 college students were coded against L. R. Goldberg's (1990) FFM factor analysis to construct personality scores for actual, ideal, and ought self domains, as well as several PBSD indices. Multivariate analyses were conducted to test self-discrepancy and personality-structure hypotheses, and to demonstrate this strategy's operational flexibility. Profile analyses indicated that empirical self-discrepancies depend upon whether and how personality structure is incorporated. Methodological alterations influenced self-discrepancy findings negligibly. Initial evidence for PBSD construct validity and predictive specificity is presented, and the approach's implications, advantages, and extensions are discussed.