Circulation of West Nile virus lineage 1 and 2 during an outbreak in Italy


Corresponding author: F. Magurano, Istituto Superiore di Sanità, Department of Infectious, Parasitic and Immunomediated Diseases, v.le Regina Elena 299 00161, Rome, Italy.


Clin Microbiol Infect 2012; 18: E545–E547


In 2011, from 26 September to 16 October, a small outbreak of West Nile virus (WNV) disease occurred on the island of Sardinia (Italy). According to the national case definition, six cases with acute neurological disease were confirmed in hospitalized patients, and four of them died; one of these was only 34 years old. In two case, WNV RNA was detected in urine, suggesting renal involvement. Sequence analysis showed lineage 1 and 2 circulation.