Mobile genetic elements of Pseudomonas aeruginosa isolates from hydrotherapy facility and respiratory infections

Authors

  • S. G. Pereira,

    1. Center for Pharmaceutical Studies, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal
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  • O. Cardoso

    Corresponding author
    1. Center for Pharmaceutical Studies, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal
    • Corresponding author: O. Cardoso, Faculty of Pharmacy of University of Coimbra, Health Sciences Campus, Azinhaga de Santa Comba, 3004–568 Coimbra, Portugal

      E-mail: ocardoso@ci.uc.pt

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Abstract

The content of mobile genetic elements in Pseudomonas aeruginosa isolates of a pristine natural mineral water system associated with healthcare was compared with clinical isolates from respiratory infections. One isolate, from the therapy pool circuit, presented a class 1 integron, with 100% similarity to a class 1 integron contained in plasmid p4800 of the Klebsiella pneumoniae Kp4800 strain, which is the first time it has been reported in P. aeruginosa. Class 1 integrons were found in 25.6% of the clinical isolates. PAGI1 orf3 was more prevalent in environmental isolates, while PAGI2 c105 and PAGI3 sg100 were more prevalent in clinical isolates. Plasmids were not observed in either population.

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