This article is based upon the Presidential Address to the Society for Psychophysiological Research, 2000. The research reported in this article was generously supported by National Institute of Mental Health Grants MH43454, MH40747, P50-MH52354, P50-MH61083, by Research Scientist Award K05-MH00875, by grants from the Research Network on Mind-Body Interaction of the John D. and Catherine T. MacArthur Foundation, and by support from the University of Wisconsin. I am deeply indebted to the many students and collaborators associated with the Laboratory for Affective Neuroscience and the WM. Keck Laboratory for Functional Brain Imaging and Behavior for making this work possible. I owe an enormous debt of gratitude to the members of my lab, without whom this sustained body of work would not at all be possible. These lab members have nourished, challenged, stimulated, questioned, and catalyzed much of what is presented in this article. The opportunity to learn from one's students is perhaps the greatest honor and privilege in the life of a practicing scientist, and for this, I am deeply grateful.
Affective neuroscience and psychophysiology: Toward a synthesis
Article first published online: 4 AUG 2003
Volume 40, Issue 5, pages 655–665, September 2003
How to Cite
Davidson, R. J. (2003), Affective neuroscience and psychophysiology: Toward a synthesis. Psychophysiology, 40: 655–665. doi: 10.1111/1469-8986.00067
- Issue published online: 4 AUG 2003
- Article first published online: 4 AUG 2003
- (Received December 27, 2002; Accepted May 2, 2003)
- Affective style;
- Affective neuroscience;
- Prefrontal cortex;
This article reviews the author's program of research on the neural substrates of emotion and affective style and their behavioral and peripheral biological correlates. Two core dimensions along which affect is organized are approach and withdrawal. Some of the key circuitry underlying approach and withdrawal components of emotion is reviewed with an emphasis on the role played by different sectors of the prefrontal cortex (PFC) and amygdala. Affective style refers to individual differences in valence-specific features of emotional reactivity and regulation. The different parameters of affective style can be objectively measured using specific laboratory probes. Relations between individual differences in prefrontal and amygdala function and specific components of affective style are illustrated. The final section of the article concludes with a brief discussion of plasticity in the central circuitry of emotion and the possibility that this circuitry can be shaped by training experiences that might potentially promote a more resilient, positive affective style. The implications of this body of work for a broader conception of psychophysiology and for training the next generation of psychophysiologists are considered in the conclusion.