Joint senior authors.
A rapid questionnaire assessment of environmental exposures to pregnant women in the INTERGROWTH-21st Project
Article first published online: 9 SEP 2013
© 2013 Royal College of Obstetricians and Gynaecologists
BJOG: An International Journal of Obstetrics & Gynaecology
Special Issue: The Methodology of the INTERGROWTH-21st Project
Volume 120, Issue Supplement s2, pages 129–138, September 2013
How to Cite
A rapid questionnaire assessment of environmental exposures to pregnant women in the INTERGROWTH-21st Project. BJOG 2013;120 (Suppl. 2): 129–138., , , , , , , , , , , , , , , , , , , , , for the International Fetal and Newborn Growth Consortium for the 21st Century (INTERGROWTH-21st).
- Issue published online: 9 SEP 2013
- Article first published online: 9 SEP 2013
- Manuscript Accepted: 19 JUL 2013
- INTERGROWTH-21st. Grant Number: 49038
- U.S. Environmental Protection Agency (US EPA). Grant Numbers: RD 83171001, RD 826709
- NIEHS. Grant Number: PO1 ES009605
- Environmental exposure;
- exposure questionnaire;
- fetal exposure;
- fetal growth;
- low birth weight;
- maternal exposure;
Impaired fetal growth and preterm birth are the leading causes of neonatal and infant mortality worldwide and there is a growing scientific literature suggesting that environmental exposures during pregnancy may play a causal role in these outcomes. Our purpose was to assess the environmental exposure of the Fetal Growth Longitudinal Study (FGLS) participants in the multinational INTERGROWTH-21st Project. First, we developed a tool that could be used internationally to screen pregnant women for such exposures and administered it in eight countries on a subsample (n = 987) of the FGLS participants. The FGLS is a study of fetal growth among healthy pregnant women living in relatively affluent areas, at low risk of adverse pregnancy outcomes and environmental exposures. We confirmed that most women were not exposed to major environmental hazards that could affect pregnancy outcomes according to the protocol's entry criteria. However, the instrument was able to identify some women that reported various environmental concerns in their homes such as peeling paint, high residential density (>1 person per room), presence of rodents or cockroaches (hence the use of pesticides), noise pollution and safety concerns. This screening tool was therefore useful for the purposes of the project and can be used to ascertain environmental exposures in studies in which the primary aim is not focused on environmental exposures. The instrument can be used to identify subpopulations for more in-depth assessment, (e.g. environmental and biological laboratory markers) to pinpoint areas requiring education, intervention or policy change.