Menstrual and fertility outcomes following the surgical management of postpartum haemorrhage: a systematic review
Article first published online: 9 DEC 2013
© 2013 Royal College of Obstetricians and Gynaecologists
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 121, Issue 4, pages 382–388, March 2014
How to Cite
Menstrual and fertility outcomes following the surgical management of postpartum haemorrhage: a systematic review. BJOG 2014;121:382–388., , , , .
- Issue published online: 17 FEB 2014
- Article first published online: 9 DEC 2013
- Manuscript Accepted: 1 OCT 2013
Uterine-sparing surgical interventions have long been practiced as an alternative to hysterectomy in the management of severe postpartum haemorrhage (PPH); however, the risks of impairment of subsequent fertility from such procedures are unclear.
To evaluate the menstrual and fertility outcomes following radiological or conservative surgical interventions for severe PPH.
A systematic review of English and non-English articles using the Cochrane Library 2012, PubMed (1950–2012), Embase (1980–2012), and the National Research Register. The keywords used for our search included ‘fertility’, ‘reproductive outcome’, ‘postpartum haemorrhage’, ‘embolisation’, ‘hypogastric artery ligation’, ‘B-Lynch suture’, ‘stepwise uterine devascularisation’, ‘tamponade’, and ‘uterine compression sutures’.
Studies including human female subjects with at least five cases.
Data collection and analysis
Independent extraction of articles by two authors using predefined data fields, including study quality indicators.
We identified 402 publications and after exclusions, 28 studies were included in the systematic review. Seventeen studies (675 women) reported on the fertility outcomes after uterine artery embolisation, five studies (195 women) reported on the fertility outcomes after uterine devascularisation, and six studies (125 women) reported on the fertility outcomes following uterine compression sutures. Overall, 553 out of 606 (91.25%) women resumed menstruation within 6 months of delivery. One hundred and eighty-three out of 235 (77.87%) women who desired another pregnancy achieved conception.
Uterine-sparing radiological and surgical techniques for the management of severe PPH do not appear to adversely affect the menstrual and fertility outcomes in most women; however, the number of studies and the quality of the available evidence is of concern.