Indications for caesarean sections at ≥34 weeks among nulliparous women and differential composite maternal and neonatal morbidity
Article first published online: 10 FEB 2014
© 2014 Royal College of Obstetricians and Gynaecologists
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 121, Issue 11, pages 1395–1402, October 2014
How to Cite
Indications for caesarean sections at ≥34 weeks among nulliparous women and differential composite maternal and neonatal morbidity. BJOG 2014;121:1395–1402., , , , , , , , , .
- Issue published online: 23 SEP 2014
- Article first published online: 10 FEB 2014
- Manuscript Accepted: 15 DEC 2013
- composite maternal or neonatal morbidity;
To compare composite maternal and neonatal morbidities (CMM, CNM) among nulliparous women with primary indications for caesarean section (CS) as acute clinical emergency (group I; ACE), non-reassuring fetal heart rate (group II) and arrest disorder (group III).
A multicentre prospective study.
Nineteen academic centres in the USA, with deliveries in 1999–2002.
Nulliparous women (n = 9829) that had CS.
Nulliparous women undergoing CS for three categories of indications were compared using logistic regression model, adjusted for five variables.
Main outcome measures
CMM was defined as the presence of any of the following: intrapartum or postpartum transfusion, uterine rupture, hysterectomy, cystotomy, ureteral or bowel injury or death; CNM was defined as the presence of any of the following: umbilical arterial pH <7.00, neonatal seizure, cardiac, hepatic, renal dysfunction, hypoxic ischaemic encephalopathy or neonatal death.
The primary reasons for CS were ACE in 1% (group I, n = 114) non-reassuring FHR in 29% (group II; n = 2822) and failed induction/dystocia in the remaining 70% (group III; n = 6893). The overall risks of CMM and CNM were 2.5% (95% confidence intervals, CI, 2.2–2.8%) and 1.9% (95% CI 1.7–2.2), respectively. The risk of CMM was higher in group I than in group II (RR 4.1, 95% CI 3.1, 5.3), and group III (RR 3.2, 95% CI 2.7, 3.7). The risk of CNM was also higher in group I than in group II (RR 2.8, 95% CI 2.3, 3.4) and group III (RR 14.1, 95% CI 10.7, 18.7).
Nulliparous women who have acute clinically emergent caesarean sections are at the highest risks of both composite maternal and neonatal morbidity and mortality.