Verification of the anatomy and newly discovered histology of the G-spot complex


  • Linked article This article is commented on by Miller CE and Puppo V, pp. 1340 and 1341 in this issue, respectively.
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  • This study was presented during the plenary session at the XX FIGO World Congress of Gynecology and Obstetrics, Rome, Italy, October 2012.



To expand the anatomical investigations of the G-spot and to assess the G-spot's characteristic histological and immunohistochemical features.


An observational study.


International multicentre.


Eight consecutive fresh human female cadavers.


Anterior vaginal wall dissections were executed and G-spot microdissections were performed. All specimens were stained with haematoxylin and eosin (H&E). The tissues of two women were selected at random for immunohistochemical staining.

Main outcome measures

The primary outcome measure was to document the anatomy of the G-spot. The secondary outcome measures were to identify the histology of the G-spot and to determine whether histological samples stained with H&E are sufficient to identify the G-spot.


The anatomical existence of the G-spot was identified in all women and was in a diagonal plane. In seven (87.5%) and one (12.5%) of the women the G-spot complex was found on the left or right side, respectively. The G-spot was intimately fused with vessels, creating a complex. A large tangled vein-like vascular structure resembled an arteriovenous malformation and there were a few smaller feeding arteries. A band-like structure protruded from the tail of the G-spot. The size of the G-spot varied. Histologically, the G-spot was determined as a neurovascular complex structure. The neural component contained abundant peripheral nerve bundles and a nerve ganglion. The vascular component comprised large vein-like vessels and smaller feeding arteries. Circular and longitudinal muscles covered the G-complex.


The anatomy of the G-spot complex was confirmed. The histology of the G-spot presents as neurovascular tissues with a nerve ganglion. H&E staining is sufficient for the identification of the G-spot complex.