Robin Knobel was paid to present research related to this subject at a National Association of Neonatal Nurses conference. The other authors report no conflict of interest or relevant financial relationships.
A Pilot Study to Examine Maturation of Body Temperature Control in Preterm Infants
Article first published online: 4 SEP 2013
© 2013 AWHONN, the Association of Women's Health, Obstetric and Neonatal Nurses
Journal of Obstetric, Gynecologic, & Neonatal Nursing
Volume 42, Issue 5, pages 562–574, September/October 2013
How to Cite
Knobel, R. B., Levy, J., Katz, L., Guenther, B. and Holditch-Davis, D. (2013), A Pilot Study to Examine Maturation of Body Temperature Control in Preterm Infants. Journal of Obstetric, Gynecologic, & Neonatal Nursing, 42: 562–574. doi: 10.1111/1552-6909.12240
- Issue published online: 10 SEP 2013
- Article first published online: 4 SEP 2013
- Manuscript Accepted: JUN 2013
- AWHONN/March of Dimes “Saving Babies, Together”
- Duke University School of Nursing Small Grant
- Jean & George Brumley Neonatal-Perinatal Institute
- NIH/NINR. Grant Number: 1R15NR01157–01
- Robert Wood Johnson Foundation Nurse Faculty Scholars. Grant Number: 68041
- Body Temperature Regulation;
- Physiological Processes;
- Pilot Projects
To test instrumentation and develop analytic models to use in a larger study to examine developmental trajectories of body temperature and peripheral perfusion from birth in extremely low-birth-weight (EBLW) infants.
A case study design.
The study took place in a Level 4 neonatal intensive care unit (NICU) in North Carolina.
Four ELBW infants, fewer than 29 weeks gestational age at birth.
Physiologic data were measured every minute for the first 5 days of life: peripheral perfusion using perfusion index by Masimo and body temperature using thermistors. Body temperature was also measured using infrared thermal imaging. Stimulation and care events were recorded over the first 5 days using video which was coded with Noldus Observer software. Novel analytical models using the state space approach to time-series analysis were developed to explore maturation of neural control over central and peripheral body temperature.
Results from this pilot study confirmed the feasibility of using multiple instruments to measure temperature and perfusion in ELBW infants. This approach added rich data to our case study design and set a clinical context with which to interpret longitudinal physiological data.