Genome-wide transcriptional responses of Fusarium graminearum to plant cell wall substrates

Authors

  • Raphaël Carapito,

    1. Laboratoire d'Ingénierie des Polymères pour les Hautes Technologies, Université de Strasbourg, ECPM, Strasbourg Cedex, France
    Current affiliation:
    1. Laboratoire d'ImmunoRhumatologie Moléculaire (INSERM UMR_S 1109), Centre de Recherche d'Immunologie et d'Hématologie, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg, Strasbourg Cedex, France
    Search for more papers by this author
  • Sonja Vorwerk,

    1. febit holding GmbH, Heidelberg, Germany
    Current affiliation:
    1. Ascendis Pharma GmbH, Heidelberg, Germany
    Search for more papers by this author
  • Jean-Marc Jeltsch,

    1. Laboratoire d'Ingénierie des Polymères pour les Hautes Technologies, Université de Strasbourg, ECPM, Strasbourg Cedex, France
    Search for more papers by this author
  • Vincent Phalip

    Corresponding author
    • Laboratoire d'Ingénierie des Polymères pour les Hautes Technologies, Université de Strasbourg, ECPM, Strasbourg Cedex, France
    Search for more papers by this author

Correspondence: Vincent Phalip, Ecole Supérieure de Biotechnologie de Strasbourg, 300, Boulevard Sébastien Brandt, BP 10413, 67412 ILLKIRCH Cedex, France. Tel.: +33 0 3 68 85 48 20; fax: +33 0 3 68 85 46 83; e-mail address: phalip@unistra.fr

Abstract

We report a genome-wide transcriptomic study of Fusarium graminearum grown on four different substrates based on plant cell wall components. About 5% of the genes were differentially expressed in at least one condition. Analysis of upregulated cell wall-degrading enzymes highlights a sharp growth medium-specific adaptation process. In particular, the nature of the polysaccharides available for fungal growth induced a specific transcriptional response aiming at the targeted enzymatic degradation of the given polysaccharides.

Ancillary