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fml12109-sup-0001-FigS1.docxWord document61KFig. S1. The effect of different concentrations of anhydrotetracycline (ATc) on growth of wild-type S. Typhimurium bearing pASK-IBA33+.
fml12109-sup-0002-FigS2.docxWord document106KFig. S2. Plasmid maps for all vectors used in this study. A. General cloning vectors. B. Overexpression plasmids constructed from the plasmids seen in part A.
fml12109-sup-0003-TableS1.docxWord document94KTable S1. Minimized sum of flux values for Δppc (Gene1) and for the top 13 double knockouts (KOs) involving ppc as ranked by priority score.
fml12109-sup-0004-TableS2.docxWord document49KTable S2. The genes shown in the table are all predicted synthetic lethal gene pairs using the genome-scale metabolic model for Salmonella Typhimurium LT2 (Thiele et al., 2011) where one of the genes is ppc.
fml12109-sup-0005-TableS3.docxWord document51KTable S3. Supplementation of glucose M9 media with different carbon sources and their effect on growth of the wild-type and Δppc mutant.

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